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Young Blood does Not Reverse Aging in Old Mice

Heterochronic blood exchange effects on muscle regeneration and performance.

Heterochronic blood exchange effects on muscle regeneration and performance.

A new study from UC Berkeley found that tissue health and repair dramatically decline in young mice when half of their blood is replaced with blood from old mice. The study argues against the rejuvenating properties of young blood and points to old blood, or molecules within, as driving the aging process. “Our study suggests that young blood by itself will not work as effective medicine,” said A/Prof Irina Conboy, Dept of Bioengineering at UC Berkeley. “It’s more accurate to say that there are inhibitors in old blood that we need to target to reverse aging.”

In 2005, Conboy et al published a study in Nature that found evidence for tissue rejuvenation in older mice when they are surgically joined to younger mice so...

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