Category Biology/Biotechnology

Soft, 3D transistors could host living cells for bioelectronics

Soft, 3D transistors may upend semiconductor device design, transform bioelectronics
From 2D rigid electronics to 3D soft electronics: Increasing the dimensionality of transistors with 3D hydrogel semiconductors. Credit: Shiming Zhang

New research from the WISE group (Wearable, Intelligent, Soft Electronics) at The University of Hong Kong (HKU-WISE) has addressed a long-standing bioelectronic challenge: the development of soft, 3D transistors.

This work introduces a new approach to semiconductor device design with transformative potential for bioelectronics. It is published in Science.

Led by Professor Shiming Zhang from the Department of Electrical and Electronic Engineering, Faculty of Engineering, the research team included senior researchers who joined HKU-WISE from the University of Cambridge and the University of Chicago, together with HKU Ph.D...

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Maternal microbiome compound may hold key to preventing liver disease

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Children born to mothers who consume a high-fat, high-sugar diet during pregnancy and breastfeeding face a higher risk of developing fatty liver disease later in life.

New research from the University of Oklahoma suggests that risk may be reduced. A recent study has found that supplementing pregnant and lactating mice with a naturally occurring compound produced by healthy gut bacteria significantly lowered rates of fatty liver disease in their offspring as they aged.

The research is published in the journal eBioMedicine.

How gut bacteria compound may help
The compound, called indole, is naturally made by healthy gut bacteria when they break down tryptophan, an amino acid found in foods such as turkey and nuts...

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Using rare sugars to address alcoholism

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How the FGF21-oxytocin-dopamine system regulates alcohol consumption. (Yoh Izumori)

While investigating the FGF21-oxytocin-dopamine system, a mechanism that regulates sugar appetite, a team of researchers at Kyoto University noticed reports suggesting that the protein FGF21 may regulate alcohol ingestion.

The team’s original aim had been to address sugar appetite in lifestyle-related diseases, but since alcohol is a fermented product of sugar, they speculated that perhaps the body contains a system that recognizes both alcohol and sugar as the same entity.

Alcohol consumption and intervention challenges
Excessive alcohol consumption is a major global health issue, and effective countermeasures for prevention and treatment are limited...

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Novel AI method sharpens 3D X-ray vision

Novel AI method sharpens 3D X-ray vision
This 3D image of an integrated circuit showing slices through its thickness was reconstructed with a new technique that incorporates artificial intelligence called the “perception fused iterative tomography reconstruction engine.” Credit: Brookhaven National Laboratory

X-ray tomography is a powerful tool that enables scientists and engineers to peer inside of objects in 3D, including computer chips and advanced battery materials, without performing anything invasive. It’s the same basic method behind medical CT scans.

Scientists or technicians capture X-ray images as an object is rotated, and then advanced software mathematically reconstructs the object’s 3D internal structure...

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