SMOX is a key node for breast oncogenesis mediated by multiple pathogenic microbes and pharmacological inhibition of SMOX can serve as an intervention strategy for breast cancer patients harboring microbial dysbiosis. Credits: Drs. Deeptashree Nandi and Dipali Sharma
Researchers at the Johns Hopkins Kimmel Cancer Center have discovered how certain pathogenic bacteria in gut and breast tissue can promote breast cancer development and progression by hijacking a key metabolic enzyme known as spermine oxidase (SMOX). In a study led by Dipali Sharma, Ph.D...
Altered brain connectivity across diagnoses. The meta-analysis revealed consistent alterations in white matter connectivity across psychosis-spectrum disorders, including schizophrenia and bipolar disorder. Credit: Merola et al.
For decades, schizophrenia and bipolar disorder (BD) were treated as distinct and unrelated psychiatric disorders. Schizophrenia is a psychiatric disorder characterized by altered thinking and emotional patterns, hallucinations, false or irrational beliefs (i.e., delusions), cognitive deficits, and disorganized speech. BD, on the other hand, is marked by extreme mood swings, ranging between periods of high-energy (i.e., mania or hypomania) and depressive episodes.
While the symptoms of schizophrenia and BD are markedly different, many patients diagnosed with...
Michael Scott Hopkins performs a microgravity experiment on the International Space Station.
If humankind is to explore deep space, one small passenger should not be left behind: microbes. In fact, it would be impossible to leave them behind, since they live on and in our bodies, surfaces and food. Learning how they react to space conditions is critical, but they could also be invaluable fellows in our endeavor to explore space.
Microorganisms such as bacteria and fungi can harvest crucial minerals from rocks and could provide a sustainable alternative to transporting much-needed resources from Earth.
Researchers from Cornell and the University of Edinburgh collaborated to study how those microbes extract platinum group elements from a meteorite in microgravity, with an experimen...
Researchers discovered that beneficial gut bacteria can sense a wide array of nutrients and chemical signals, guiding them toward the best food sources. Credit: Shutterstock
Your gut bacteria are chemical detectives—sniffing out nutrients and even feeding each other to keep your microbiome thriving. Your gut is home to trillions of bacteria that constantly “sense” their surroundings to survive and thrive. New research shows that beneficial gut microbes, especially common Clostridia bacteria, can detect a surprisingly wide range of chemical signals produced during digestion, including byproducts of fats, proteins, sugars, and even DNA. These microbes use specialized sensors to move toward valuable nutrients, with lactate and formate standing out as especially important fuel sources...
Recent Comments