Category Biology/Biotechnology

PAINTing a Wound-healing Ink into Cuts with a 3D printing Pen

PAINTing a wound-healing ink into cuts with a 3D-printing pen
This 3D printing pen is painting a gel that can help wounds of all shapes heal quickly and effectively. Credit: Adapted from ACS Applied Materials & Interfaces, 2023, DOI: 10.1021/acsami.3c03630

The body is pretty good at healing itself, though more severe wounds can require bandages or stitches. But researchers publishing in ACS Applied Materials & Interfaces have developed a wound-healing ink that can actively encourage the body to heal by exposing the cut to immune-system vesicles. The ink can be spread into a cut of any shape using a 3D-printing pen, and in mice, the technology nearly completely repaired wounds in just 12 days.

When the skin is cut or torn, the body’s natural “construction crew” kicks in to fix it back up—clearing out any bacterial invaders, regrowing broken blo...

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Low-Flavanol Diet drives Age-related Memory Loss, Large Study finds

A large-scale study led by researchers at Columbia and Brigham and Women’s Hospital/Harvard is the first to establish that a diet low in flavanols—nutrients found in certain fruits and vegetables—drives age-related memory loss.

The study found that flavanol intake among older adults tracks with scores on tests designed to detect memory loss due to normal aging and that replenishing these bioactive dietary components in mildly flavanol-deficient adults over age 60 improves performance on these tests.

“The improvement among study participants with low-flavanol diets was substantial and raises the possibility of using flavanol-rich diets or supplements to improve cognitive function in older adults,” says Adam Brickman, Ph.D...

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Super Low-cost Smartphone Attachment brings Blood Pressure Monitoring to your Fingertips

Two hands hold a black smartphone against a white background.
Prototype of the blood pressure monitoring clip. The user presses on the clip and a custom smartphone app guides the user on how hard and long to press during the measurement. Photos courtesy of the Digital Health Lab / UC San Diego.

Engineers at the University of California San Diego have developed a simple, low-cost clip that uses a smartphone’s camera and flash to monitor blood pressure at the user’s fingertip. The clip works with a custom smartphone app and currently costs about 80 cents to make. The researchers estimate that the cost could be as low as 10cents apiece when manufactured at scale.

The technology was published May 29 in Scientific Reports.

Researchers say it could help make regular blood pressure monitoring easy, affordable and accessible to people in resource-p...

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Cancers in Distant Organs Alter Liver Function

Tumor cell-derived EVPs induced accumulation of lipid droplets in the mouse liver. Green, lipid droplet. Blue, DAPI. Credit: Gang Wang, Jianlong Li, David Lyden.
Tumor cell-derived EVPs induced accumulation of lipid droplets in the mouse liver. Green, lipid droplet. Blue, DAPI. Credit: Gang Wang, Jianlong Li, David Lyden.

Cancers often release molecules into the bloodstream that pathologically alter the liver, shifting it to an inflammatory state, causing fat buildup and impairing its normal detoxifying functions, according to a study from investigators at Weill Cornell Medicine. This discovery illuminates one of cancer’s more insidious survival mechanisms and suggests the possibility of new tests and drugs for detecting and reversing this process.

In the study, published May 24 in Nature, the researchers found that a wide variety of tumor types growing outside the liver remotely reprogram the liver to a state resembling fatty liver disease ...

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