Category Biology/Biotechnology

A new University of Arizona Health Sciences study found that people older than 45yo whose Type 2 diabetes was treated with anti-hyperglycemic medications had an increased risk of multiple sclerosis, particularly among women, while anti-hyperglycemic exposure in people younger than 45 reduced that risk.

“Our findings reinforce the need for a precision medicine approach to preventing MS in these vulnerable populations,” said lead researcher Kathleen Rodgers, PhD, associate director of translational neuroscience at the Center for Innovation in Brain Science.

Multiple sclerosis (MS) is an unpredicta...

A research team has identified a molecular target that could open up new therapeutic options to treat aging-associated diseases like Parkinson’s. Scientists at the University of Cologne have discovered how cells can eliminate mutated mitochondrial DNA (mtDNA). Mitochondria are the powerhouses of our cells. Due to their evolutionary descent from bacteria, they still have genetic material packaged in chromosome-like structures (nucleoids). They convert the chemical energy in our food into a biologically usable form...

A Cup of ruby red hibiscus tea not only warms the body in winter but also is known to boost the immune system, control blood pressure, and reduce body weight. And here is yet another reason to enjoy this tea – It may defeat Alzheimer’s disease.

Professor Kyong-Tai Kim and PhD candidate Kyung Won Jo (Department of Life Sciences) at POSTECH has verified that the gossypetin found in hibiscus activates microglia, the resident immune cell in the brain. The research team also demonstrated that microglia scavenge amyloid-beta (Aβ) in the brain to ameliorate cognitive impairments brought on by Alzheimer’s disease (AD).

AD begins as Aβ and Tau protein aggregates form deposits in the brain tissue. Microglia internalize such aggregates (phagocytosis) to protect the brain...

E-cigarettes and marijuana have harmful effects on the heart similar to those caused by tobacco cigarettes, opening the door to abnormal heart rhythms, reports a team of researchers at UC San Francisco.

The study is published November 15, 2022 in the journal Heart Rhythm.

“We found that cigarettes, e-cigarettes, and marijuana greatly interfere with the electrical activity, structure, and neural regulation of the heart,” said lead author Huiliang Qiu, MD, Ph.D., a postdoctoral scholar in the UCSF Division of Cardiology. “Often, any single change can lead to arrhythmia disease. Unfortunately, these adverse effects on the heart are quite comprehensive.”

For the heart to work well, it must pump blood efficiently and with correct timing...