Category Biology/Biotechnology

In DNA, scientists find solution to building Superconductor that could Transform Technology

UVA's Edward H. Egelman, PhD, has been elected to the prestigious National Academy of Sciences.
UVA’s Edward H. Egelman, PhD, was elected to the prestigious National Academy of Sciences in recognition of his research accomplishments.

Scientists at the University of Virginia School of Medicine and their collaborators have used DNA to overcome a nearly insurmountable obstacle to engineer materials that would revolutionize electronics.

One possible outcome of such engineered materials could be superconductors, which have zero electrical resistance, allowing electrons to flow unimpeded i.e. they don’t lose energy and don’t create heat, unlike current means of electrical transmission...

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Using Light to Restore Cell Function

A super resolution image captured in Diao’s lab shows the endoplasmic reticulum in green, lysosomes in pink and mitochondria in red. Using the light-activated proteins, the mitochondria and lysosomes are brought together to conduct mitochondrial fission. Photo provided by Jiajie Diao.

New research from the University of Cincinnati shows early indications that light can be used as a treatment for certain diseases, including cancer.

Researchers from UC, the U222niversity of Illinois Urbana-Champaign and the University at Buffalo published the results of their study demonstrating light-activated proteins can help normalize dysfunction within cells in the journal Nature Communications July 25.

The research centers on the functions of mitochondria, organelles within a cell that act as...

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Fast-acting Immune Cells provide Powerful Protection against Stroke

CREDIT: Adapted from Cai and Shi et al., 2022
CAPTION:  Within 24 hours after researchers depleted CD8+TRLs from the bloodstream of stroke mice, the size of the brain region affected by ischemia expanded by 50% (middle panel) compared to animals whose CD8+TRL levels remained intact (left and right panels).

CD8+ regulatory-like Tcells reach the brain within 24 hours after stroke onset, where they release molecules that provide direct neuroprotective effects, as well as limit inflammation and secondary brain damage.

“The beauty of CD8+TRLs is in their fast response. They confer very potent protection to the brain, which can last a long time,” said co-corresponding author Xiaoming Hu, M.D., Ph.D., associate professor of neurology at Pitt and a U.S...

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New link found that connects Cell Signaling Pathway to Development of Esophageal Cancers, Barrett’s Syndrome

Researchers believe pathway is a potential therapeutic target for gastroesophageal cancers. A team of researchers believe they have identified a cell signaling pathway responsible for the development of esophageal adenocarcinomas, an aggressive form of esophageal cancer that has gradually become more common, even in younger people.

Of the roughly 20,000 people in the U.S. diagnosed with esophageal cancer this year, just 4,000 are likely to still be alive in 2027. Such dire data has long driven researchers to try to understand the roots of the disease, but they have discovered little — until now.

“The incidence of esophageal cancers has increased several fold over the last few decades, making it the most common esophageal malignancy in the U.S...

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