Category Biology/Biotechnology

A humble Brazilian coastal plant used in folk medicine is now backed by science as a potential natural fighter against inflammation and arthritis.

A research team in Brazil has found strong evidence that the Joseph’s Coat plant (Alternanthera littoralis) is both safe and effective at reducing inflammation, easing pain, and protecting against arthritis. The study was carried out by scientists from the Federal University of Grande Dourados (UFGD), the State University of Campinas (UNICAMP), and São Paulo State University (UNESP).

Joseph’s Coat grows naturally along Brazil’s coastline and has long been used in tradi...

Researchers have developed experimental drugs that encourage the mitochondria in our cells to work a little harder and burn more calories. The findings could open the door to new treatments for obesity and improve metabolic health.

Obesity is a global epidemic and a risk factor for many diseases, including diabetes and cancer. Current obesity drugs require injections and can cause side effects, so a safe way to boost weight loss could deliver significant public health benefits.

The study, led by Associate Professor Tristan Rawling from the University of Technology Sydney (UTS), has just been published in Chemical Science, where it was highlighted as “pick of the week.”

How mitochondrial uncouplers work
The research team, from UTS and ...

Temporal lobe epilepsy, which results in recurring seizures and cognitive dysfunction, is associated with premature aging of brain cells.

A new study by researchers at Georgetown University Medical Center found that this form of epilepsy can be treated in mice by either genetically or pharmaceutically eradicating the aging cells, thereby improving memory and reducing seizures as well as protecting some animals from developing epilepsy.

The study appears in the journal Annals of Neurology.

Current challenges and hopes for treatment
“A third of individuals living with epilepsy don’t achieve freedom from seizures with current medications,” says senior author Patrick A. Forcelli, Ph.D...

A hidden protein helper may play a key role in why hunger control works for some people but not others. Researchers have identified a previously overlooked protein that helps regulate appetite and energy use in the body. This “helper” protein supports a key system that decides whether the body burns energy or stores it, and when it does not function properly, appetite signals can weaken.

New research suggests that a protein the body relies on to manage appetite and energy levels cannot function on its own. Instead, it depends on a partner protein to work properly...