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    Category Biology/Biotechnology

    Researchers Identify Potential New Treatment for Metabolic Syndrome

    April 12, 2022, Categories  Health/Medical, Biology/Biotechnology

    Highlights
    •Protein tyrosine phosphatase receptor δ is the orexigenic asprosin receptor
    •Ptprd loss results in appetite reduction and unresponsiveness to exogenous asprosin
    •AgRP neuron-specific Ptprd ablation leads to protection from diet-induced obesity
    •The Ptprd ligand-binding domain functions as an appetite-suppressing therapeutic

    Metabolic syndrome increases a person’s risk for diabetes, heart disease, and stroke, and includes conditions such as obesity, high blood pressure and high blood sugar...

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    Old Skin Cells Reprogrammed to Regain Youthful Function

    April 9, 2022, Categories  Health/Medical, Biology/Biotechnology

    Research from the Babraham Institute has developed a method to “time jump” human skin cells by 30 years, turning back the aging clock for cells without losing their specialized function. Work by researchers in the Institute’s Epigenetics research program has been able to partly restore the function of older cells, as well as rejuvenating the molecular measures of biological age. The research is published today in the journal eLife, and while this topic is still at an early stage of exploration, it could revolutionize regenerative medicine.

    What is regenerative medicine?

    As we age, our cells’ ability to function declines and the genome accumulates marks of aging. Regenerative biology aims to repair or replace cells including old ones...

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    New technique uses the Body’s Naturally Occurring Ions to help Transmit Data Wirelessly

    April 8, 2022, Categories  Health/Medical, Biology/Biotechnology, Technology/Electronics

    Ionic communication: (Top left) Cross-sectional schematic illustration of an ionic communication device consisting of an implanted transmitter electrode pair inside biological tissue and a receiver electrode pair on the surface of the tissue. (Top right) Frequency responses of ionic communication highlighting is capacity to operate at megarhertz frequencies. A 10-link ionic communication transmitter (TX) and receiver (RX) array conforming to the surface of an orchid petal. Credit: Dion Khodagholy/Columbia Engineering

    Implantable bioelectronics are now often key in assisting or monitoring the heart, brain, and other vital organs, but they often lack a safe, reliable way of transmitting their data to doctors...

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    Biodegradable Gel boosts Immune System’s Attack on Several Cancers in Mice

    April 7, 2022, Categories  Health/Medical, Biology/Biotechnology

    A high-magnification of the hydrogel (in blue) encapsulating T cell-activating platelets (in red) and nanoparticles that release a drug to inhibit tumor-boosting cells (in green). This gel inhibited the growth of cancer cells after surgical removal of different types of tumors. Credit: UW–Madison

    A new biodegradable gel improves the immune system’s ability to keep cancer at bay after tumors are surgically removed. The gel, tested in mice, releases drugs and special antibodies that simultaneously deplete immune-blocking cells called macrophages from the surgical site and activate Tcells so they can attack cancer.

    University of Wisconsin–Madison scientists tested the gel on mouse models of several cancers...

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