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    Category Biology/Biotechnology

    Scientists reveal the Mechanism of Skeletal Muscle Stem Cell Activation in Muscle Regeneration

    February 25, 2022, Categories  Health/Medical, Biology/Biotechnology

    Discordant proteomic and transcriptomic signatures reveal a potential translational control mechanism during the SC quiescence-to-activation transition. a Schematic illustration of the workflow for the proteomic analysis of FACS-isolated SCs. The SCs were sorted from Pax7-nGFP mice. QSCs were sorted from 0.5% PFA-perfused mice. fiSCs were sorted from unperfused mice. Injured ASCs (iASCs) were sorted from 3 days 1.2% BaCl2 injured mice. Cultured ASCs (cASCs) were 2 days cultured SCs. (n = 2 independent experiments). b Hierarchical clustering of the protein expression (in the number of spectra) for QSCs, fiSCs, iASCs, and cASCs. c Heatmap of representative expression for cell cycle, quiescence, and activation-specific proteins of QSCs, fiSCs, iASCs, and cASCs...
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    A Type of Virus present in the Gut Microbiota is Associated with Better Cognitive Ability in Humans, Mice and Flies

    February 24, 2022, Categories  Health/Medical, Biology/Biotechnology

    Study finds a greater presence of these viruses in people who eat dairy products in their regular diet. New research associates the presence of Caudovirales in gut microbiota to an improvement in cognitive functions and memory in humans, mice and flies. The article, published in the journal Cell Host & Microbe, was led by Dr. Jordi Mayneris-Perxachs and Dr. José Manuel Fernández-Real, of the Nutrition, Eumetabolism and Health group of the Girona Biomedical Research Institute (IDIBGI) Dr. Josep Trueta and CIBEROBN, and has been carried out in collaboration with the Neuropharmacology research group led by Dr...

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    Connecting Science to Medicine: Tendon-like Tissue created from Human Stem Cells

    February 23, 2022, Categories  Health/Medical, Biology/Biotechnology

    Researchers develop artificial tendons in vitro from human stem cells that could fix common tendon injuries such as Achilles tendon rupture. Tendons are tissues that connect muscles to bones and are important for movement and locomotion. Injuries to tendons are quite common, with millions of people — particularly athletes — affected worldwide, and can often take many months to recover from, significantly impacting quality of life. Furthermore, while many options for treatment exist, none of them are perfect cures and many result in pain, immunogenicity, or long-term treatment failure. Therefore, a novel therapeutic strategy for tendon repair is needed.

    In a study published in the Journal of Tissue Engineering in January 2022, researchers from Tokyo Medical and Dental University (TM...

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    Self-Healing Materials for Robotics made from ‘Jelly’ and Salt

    February 22, 2022, Categories  Health/Medical, Biology/Biotechnology

    Researchers have developed self-healing, biodegradable, 3D-printed materials that could be used in the development of realistic artificial hands and other soft robotics applications.

    The low-cost jelly-like materials, developed by researchers at the University of Cambridge, can sense strain, temperature and humidity. And unlike earlier self-healing robots, they can also partially repair themselves at room temperature.

    The results are reported in the journal NPG Asia Materials.

    Soft sensing technologies could transform robotics, tactile interfaces and wearable devices, among other applications. However, most soft sensing technologies aren’t durable and consume high amounts of energy.

    “Incorporating soft sensors into robotics allows us to get a lot more information from them...

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