Category Biology/Biotechnology

Researchers Create Self-Sustaining, Intelligent, Electronic Microsystems from Green Material

electronic microsystem
A UMass Amherst research team has developed an electronic microsystem made from protein nanowires, a “green” electronic material that is renewably produced from microbes without producing “e-waste.”

A research team from the University of Massachusetts Amherst has created an electronic microsystem that can intelligently respond to information inputs without any external energy input, much like a self-autonomous living organism. The microsystem is constructed from a novel type of electronics that can process ultralow electronic signals and incorporates a device that can generate electricity “out of thin air” from the ambient environment.

The groundbreaking research was published June 7 in the journal Nature Communications.

Jun Yao, an assistant professor in the electrical and compu...

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Researchers identify a Molecule Critical to Functional Brain Rejuvenation

diagram showing the impact of TET1 in young and old mice
In young adult mice (left), TET1 is active in oligodendroglial cells especially after injury and this leads to new myelin formation and healthy brain function. In old mice (right), the age-related decline of TET1 levels impairs the ability of oligodendroglial cells to form functional new myelin. The authors are currently investigating whether increasing TET1 levels in older mice could rejuvenate the oligodendroglial cells and restore their regenerative functions.

The discovery could have important implications for the health of aging brains and development of therapies for neurodegenerative diseases. Recent studies suggest that new brain cells are being formed every day in response to injury, physical exercise, and mental stimulation...

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New study further Advances the Treatment of Chronic Pain

New study further advances the treatment of chronic pain
Pinwheel flower. Credit: LIH

Scientists have demonstrated that conolidine, a natural painkiller derived from the pinwheel flower and traditionally used in Chinese medicine, interacts with the newly identified opioid receptor ACKR3/ CXCR7 that regulates opioid peptides naturally produced in the brain. The researchers also developed a synthetic analogue of conolidine, RTI-5152-12, which displays an even greater activity on the receptor.

These findings, which were published on June 3rd in the international journal Signal Transduction and Targeted Therapy (Nature publishing group), further advance the understanding of pain regulation and open alternative therapeutic avenues for the treatment of chronic pain.

Opioid peptides are small proteins that mediate pain relief and emotions, in...

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Studies reveal Skull as unexpected source of Flexoelectric Brain Immunity

A newly developed B cell (green in middle of image) migrates from the bone marrow of the skull, where a cluster of other new B cells remain, then through the skull bone, to the protective tissue that covers the brain, which is populated mainly by other cells (blue). Researchers at Washington University School of Medicine in St. Louis have discovered that the immune cells stationed in the protective tissue known as the meninges come primarily from the skull. The finding opens up the possibility of developing therapies to target such cells as a way to prevent or treat brain conditions.

Immune cells from skull bone marrow guard the brain, spinal cord. Researchers have discovered that the immune cells that protect the brain and spinal cord come primarily from the skull...

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