Category Biology/Biotechnology

Stable, Efficient, Anode-free Sodium Battery

Bingyuan Ma holding a transparent capillary cell. Bai’s Lab at the McKelvey School of Engineering is the only one in the world with such diagnostic cells. (Courtesy: Bai Lab)

One-of-a-kind tool helped solve anode puzzle that thwarted previous attempts. The Washington University in St. Louis lab of Peng Bai, assistant professor in the Department of Energy, Environmental & Chemical Engineering in the McKelvey School of Engineering, has developed a stable sodium ion battery that is highly efficient, will be less expensive to make and is significantly smaller than a traditional lithium ion battery due to the elimination of a once-necessary feature.
“We’ve found that the minimal is maximum,” Bai said. “No anode is the best anode.”
The research was published May 3, 2021, in the journal Advan...

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Avocado discovery may point to Leukemia Treatment

man seated before several avocados and holding half an avocado in his right hand
Dr. Paul Spagnuolo

A compound in avocados may ultimately offer a route to better leukemia treatment, says a new University of Guelph study.

The compound targets an enzyme that scientists have identified for the first time as being critical to cancer cell growth, said Dr. Paul Spagnuolo, Department of Food Science.

Published recently in the journal Blood, the study focused on acute myeloid leukemia (AML), which is the most devastating form of leukemia. Most cases occur in people over age 65, and fewer than 10 per cent of patients survive five years after diagnosis.

Leukemia cells have higher amounts of an enzyme called VLCAD involved in their metabolism, said Spagnuolo.

“The cell relies on that pathway to survive,” he said, explaining that the compound is a likely candidate ...

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Will your Future Clothes be Made of Algae?

A mini T-shirt demonstrates the photosynthetic living materials created in the lab of Rochester biology professor Anne S. Meyer using 3D printers and a new bioink technique. (University of Rochester photo)

For the first time, an international team of researchers from the University of Rochester and Delft University of Technology in the Netherlands used 3D printers and a novel bioprinting technique to print algae into living, photosynthetic materials that are tough and resilient. The material has a variety of applications in the energy, medical, and fashion sectors. The research is published in the journal Advanced Functional Materials.

“Three-dimensional printing is a powerful technology for fabrication of living functional materials that have a huge potential in a wide range of env...

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Preclinical Discovery Triggers Wound Healing, Skin Regeneration

Difficult-to-treat, chronic wounds in preclinical models healed with normal scar-free skin after treatment with an acellular product discovered at Mayo Clinic. Derived from platelets, the purified exosomal product, known as PEP, was used to deliver healing messages into cells of preclinical animal models of ischemic wounds. The Mayo Clinic research team documented restoration of skin integrity, hair follicles, sweat glands, skin oils and normal hydration.

Ischemic wounds occur when arteries are clogged or blocked, preventing important nutrients and oxygen from reaching the skin to drive repair. This groundbreaking study titled, “TGF-β Donor Exosome Accelerates Ischemic Wound Healing,” is published in Theranostics.

“This paper documents that PEP, an off-the-shelf, room-temperatu...

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