Category Biology/Biotechnology

Blocking the activity of a fat-regulating enzyme in the muscles of mice leads to an increased capacity for endurance exercise, according to the results of a new study. Sugars and fats are the primary fuels that power every cell, tissue and organ. For most cells, sugar is the energy source of choice, but when nutrients are scarce, such as during starvation or extreme exertion, cells will switch to breaking down fats instead.

The mechanisms for how cells rewire their metabolism in response to changes in resource availability are not yet fully understood, but new research reveals a surprising consequence when one such mechanism is turned off: an increased capacity for endurance (exercise.

In a study published in the Aug...

In a mouse study, researchers have found that an antibody that targets the protein TREM2 empowers tumor-destroying immune cells and improves the effectiveness of cancer immunotherapy.

Immunotherapy has revolutionized cancer treatment by stimulating the patient’s own immune system to attack cancer cells, yielding remarkably quick and complete remission in some cases...

As the world awaits vaccines to bring the COVID-19 pandemic under control, UC San Francisco scientists have devised a novel approach to halting the spread of SARS-CoV-2, the virus that causes the disease.

Led by UCSF graduate student Michael Schoof, a team of researchers engineered a completely synthetic, production-ready molecule that straitjackets the crucial SARS-CoV-2 machinery that allows the virus to infect our cells...

Researchers have devised a test for face masks to show which are the best at blocking droplets of fluid – and rated several current options.

In a proof-of-concept study, scientists at Duke University in Durham, North Carolina, devised a low-cost laser sensor that could spot the masks that were best at stopping droplets spreading.

The team led by Eric Westman found that medical-grade ‘N95’ masks and surgical masks performed extremely well.

Handmade cotton masks also performed well, eliminating a substantial amount of the spray from normal speech.

But improvised face coverings such as bandanas and balaclava-style face coverings were less effective, the researchers found.

Duke researchers created an ine...