Category Biology/Biotechnology

Researchers 3D print Biomedical Parts with Supersonic Speed

Cells adhering to titanium alloy
This image shows cells adhering to a titanium alloy created by cold-spray 3D printing, which demonstrates the material’s biocompatibility.

Forget glue, screws, heat or other traditional bonding methods. A Cornell University-led collaboration has developed a 3D printing technique that creates cellular metallic materials by smashing together powder particles at supersonic speed.

This form of technology, known as “cold spray,” results in mechanically robust, porous structures that are 40% stronger than similar materials made with conventional manufacturing processes. The structures’ small size and porosity make them particularly well-suited for building biomedical components, like replacement joints.

The team’s paper, “Solid-State Additive Manufacturing of Porous Ti-6Al-4V by Supe...

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Bringing Drugs to the brain with Nanoparticles to treat Neurodegenerative diseases

After several years of research on effective and safe nanoparticles, the research team will continue laboratory testing, targeting the delivery of active ingredients to other animal models with ultimate clinical applications.

Researchers from the Institut national de la recherche scientifique (INRS) have shown that nanoparticles could be used to deliver drugs to the brain to treat neurodegenerative diseases.

The blood-brain barrier is the main obstacle in treating neurodegenerative diseases such as Alzheimer and Parkinson. According to a recent study conducted by Jean-Michel Rabanel, a postdoctoral researcher under the supervision of Professor Charles Ramassamy, nanoparticles with specific properties could cross this barrier and be captured by neuronal cells...

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Scientists create Hybrid Tissue construct for Cartilage Regeneration

Abstract Image
3D Bioprinted Highly Elastic Hybrid Constructs for Advanced Fibrocartilaginous Tissue Regeneration

Wake Forest Institute for Regenerative Medicine scientists (WFIRM) have developed a method to bioprint a type of cartilage that could someday help restore knee function damaged by arthritis or injury.

This cartilage, known as fibrocartilage, helps connect tendons or ligaments or bones and is primarily found in the meniscus in the knee. The meniscus is the tough, rubbery cartilage that acts as a shock absorber in the knee joint. Degeneration of the meniscus tissue affects millions of patients and arthroscopic partial meniscectomy is one of the most common orthopedic operations performed. Besides surgery, there is a lack of available treatment options.

In this latest proof-of-concept ...

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Nature-inspired design: Mimicking Moth Eyes to produce Transparent Anti-reflective Coatings

Nature-Inspired Design: Mimicking Moth Eyes to Produce Transparent Anti-Reflective Coatings
Scanning electron microscopy images of an anti-reflective thin film produced using the bio-inspired nanostructured mold (Photo courtesy: Jun Taniguchi, Tokyo University of Science)

There are many human problems that scientists and engineers have solved by drawing ideas directly from biomechanisms found in other lifeforms, from Velcro to Japan’s famous bullet trains, the Shinkansen. Thus, it should not come as a surprise to know that many remarkable advances in anti-reflective coating were inspired by the peculiar biostructures found in moth eyes.

As mainly nocturnal animals that wish to stay hidden from predators, moths have evolved to develop eyes that are non-reflective. Their eyes have a periodic nanometric structure that makes the eye surface graded, as opposed to polished...

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