Category Biology/Biotechnology

New Insights into Lung Tissue in COVID-19 disease

Sections through the three-dimensional reconstruction volume (upper left, grey) around a pulmonary alveolus with hyaline membrane (lower left, yellow). On the right, the images are superimposed. In the centre is the air bubble (alveolus). The electron density is represented by different shades of grey. On the inside of the air bubble is a layer of proteins and dead cell residues, the “hyaline membrane”. This deposit, which can be represented in its three-dimensional structure for the first time by the new method, reduces the gas exchange and leads to respiratory distress.

Photo: Tim Salditt, Marina Eckerman

Physicists at the University of Göttingen, together with pathologists and lung specialists at the Medical University of Hannover, have developed a 3D imaging technique that enables h...

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Mild COVID-19 cases can produce strong T cell Response

SARS-CoV-2 , COVID-19
Colorized scanning electron micrograph of a cell (blue) heavily infected with SARS-CoV-2 virus particles (red), isolated from a patient sample. Image captured at the NIAID Integrated Research Facility (IRF) in Fort Detrick, Maryland. Credit: NIAID

Mild cases of coronavirus disease 2019 (COVID-19) can trigger robust memory T cell responses, even in the absence of detectable virus-specific antibody responses, researchers report August 14 in the journal Cell. The authors say that memory T cell responses generated by natural exposure to or infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)—the virus that causes COVID-19—may be a significant immune component to prevent recurrent episodes of severe disease.

“We are currently facing the biggest global health emerge...

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The secret of Lymph: How Lymph Nodes help Cancer Cells spread

weight scale
The study found that melanoma cells (above) pass through the lymph nodes and pick up a protective coating, allowing them to survive high levels of oxidative stress and go on to form distant tumors.

For decades, physicians have known that many kinds of cancer cells often spread first to lymph nodes before traveling to distant organs through the bloodstream. New research from Children’s Medical Center Research Institute at UT Southwestern (CRI) provides insight into why this occurs, opening up new targets for treatments that could inhibit the spread of cancer.

The study, published today in Nature, found melanoma cells that pass through the lymph nodes pick up a protective coating, allowing them to survive high levels of oxidative stress in the blood and go on to form distant tumors.

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Multivitamin, mineral supplement linked to Less-Severe, Shorter-lasting Illness Symptoms

multivitamins

Older adults who took a daily multivitamin and mineral supplement with zinc and high amounts of vitaminC in a 12-week study experienced sickness for shorter periods and with less severe symptoms than counterparts in a control group receiving a placebo.

The findings by Oregon State University researchers were published in the journal Nutrients.

The research by scientists at OSU’s Linus Pauling Institute involved 42 healthy people ages 55 to 75 and was designed to measure the supplement’s effects on certain immune system indicators. It also looked at bloodstream levels of zinc and vitamins C and D while taking the supplement, as these micronutrients are important for proper immune function.

The immune indicators, including white blood cells’ ability to kill incoming pathogens, ...

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