Category Biology/Biotechnology

Advances in production of Retinal Cells for treating Blindness

Retinal cells stained for the identified surface marker CD140b in green (image from Fredrik Lanner’s research group)

Researchers at Karolinska Institutet and St Erik Eye Hospital in Sweden have discovered a way to refine the production of retinal cells from embryonic stem cells for treating blindness in the elderly. Using the CRISPR/Cas9 gene editing, they have also managed to modify the cells so that they can hide from the immune system to prevent rejection. The studies are published in the scientific journals Nature Communications and Stem Cell Reports.

Age-related macular degeneration of the eye is the most common cause of blindness in the elderly...

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New Quantum Technology could help Diagnose and Treat Heart Condition

ECG
Heartbeat pulse (credit: Public Domain Pictures, source: Pixabay)

The conductivity of living organs, such as the heart, could be imaged non-invasively using quantum technology, which has the potential to revolutionize the diagnosis and treatment of atrial fibrillation. Atrial fibrillation (AF) is a heart condition that causes an irregular and abnormally fast heart rate, potentially leading to blood clots, stroke, heart failure and other heart-related complications. While the causes of AF are unknown, it affects around one million people in the UK with cases predicted to rise at a great cost to the NHS.

Currently, AF is commonly diagnosed using an electrocardiogram (ECG), but this can only be done during an episode, so complementary means of diagnosis are needed.

AF is treated thr...

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On Mars or Earth, Biohybrid can turn Carbon Dioxide into New Products

A device to capture carbon dioxide from the air and convert it to useful organic products. On left is the chamber containing the nanowire/bacteria hybrid that reduces CO2 to form acetate. On the right is the chamber where oxygen is produced. (UC Berkeley photo by Peidong Yang)

Bacteria on nanowires convert sunlight, carbon dioxide and water to organic building blocks. Chemists have created a hybrid system of bacteria and nanowires that captures energy from sunlight and transfers it to the bacteria to turn carbon dioxide and water into organic molecules and oxygen. On Earth, such a biohybrid could remove carbon dioxide from the atmosphere. On Mars, it would provide colonists with raw material to manufacture organic compounds ranging from fuels to drugs...

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Old Human Cells Rejuvenated with Stem Cell technology

 Transient OSKMNL expression restores aged muscle stem cell potency.

Old human cells return to a more youthful and vigorous state after being induced to briefly express a panel of proteins involved in embryonic development, according to a new study by researchers at the Stanford University School of Medicine.

The researchers also found that elderly mice regained youthful strength after their existing muscle stem cells were subjected to the rejuvenating protein treatment and transplanted back into their bodies.

The proteins, known as Yamanaka factors, are commonly used to transform an adult cell into what are known as induced pluripotent stem cells, or iPS cells...

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