Category Biology/Biotechnology

Artificial Intelligence yields new Antibiotic

MIT researchers used a machine-learning algorithm to identify a drug called halicin that kills many strains of bacteria. Halicin (top row) prevented the development of antibiotic resistance in E. coli, while ciprofloxacin (bottom row) did not.

Image: courtesy of the Collins Lab at MIT

A deep-learning model identifies a powerful new drug that can kill many species of antibiotic-resistant bacteria

Using a machine-learning algorithm, MIT researchers have identified a powerful new antibiotic compound. In laboratory tests, the drug killed many of the world’s most problematic disease-causing bacteria, including some strains that are resistant to all known antibiotics. It also cleared infections in two different mouse models.

The computer model, which can screen more than a hundr...

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Surgeons successfully Treat Brain Aneurysms using a Robot

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Dr. Vitor Mendes Pereira views images from remote control stent placement for a brain aneurysm. Credit: Roger Boyle

A robot was used to treat brain aneurysms for the first time. The robotic system could eventually allow remote surgery, enabling surgeons to treat strokes from afar. Using a robot to treat brain aneurysms is feasible and could allow for improved precision when placing stents, coils and other devices, according to late breaking science presented today at the American Stroke Association’s International Stroke Conference 2020 . The conference, Feb. 19-21 in Los Angeles, is a world premier meeting for researchers and clinicians dedicated to the science of stroke and brain health.

Robotic technology is used in surgery and cardiology, but not for brain vascular procedures...

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Magnet-controlled Bioelectronic Implant could relieve Pain

Rice introduced the first neural implant that can be programmed and charged remotely with a magnetic field at the International Solid-State Circuits Conference. (Credit: Secure and Intelligent Micro-Systems Lab/Rice University)

Engineer’s MagNI can be wirelessly charged and programmed with magnetic fields

A team of Rice University engineers has introduced the first neural implant that can be both programmed and charged remotely with a magnetic field. Their breakthrough may make possible embedded devices like a spinal cord-stimulating unit with a battery-powered magnetic transmitter on a wearable belt.

The integrated microsystem, called MagNI (for magnetoelectric neural implant), incorporates magnetoelectric transducers...

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Antioxidant in Mushrooms may relieve features of ‘Pregnancy Hypertension’

L-( )-Ergothioneine Significantly Improves the Clinical Characteristics of Preeclampsia in the Reduced Uterine Perfusion Pressure Rat ModelHypertension, 2020; 75 (2): 561 DOI: 10.1161/HYPERTENSIONAHA.119.13929

A new study in rats suggests that the natural antioxidant L-ergothioneine could alleviate the characteristics of pre-eclampsia. Pregnancy hypertension, or Pre-eclampsia, is a complex disorder of pregnancy. Treatment of elevated blood pressure can manage the condition in the mother, but in severe cases delivery is needed, which can present a major problem to the baby if it is born prematurely.

Now, research from the Department of Pharmacology & Therapeutics at University College Cork (UCC), the INFANT Centre at UCC and the University of Liverpool, as well as The Novo Nordis...

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