Category Biology/Biotechnology

Dietary Cholesterol or Egg consumption do not increase the risk of Stroke, Finnish study finds

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Egg consumption, cholesterol intake, and risk of incident stroke in men: the Kuopio Ischaemic Heart Disease Risk Factor StudyThe American Journal of Clinical Nutrition, 2019; DOI: 10.1093/ajcn/nqz066

A new study from the University of Eastern Finland shows that a moderately high intake of dietary cholesterol or consumption of up to one egg per day is not associated with an elevated risk of stroke. Furthermore, no association was found in carriers of the APOE4 phenotype, which affects cholesterol metabolism and is remarkably common among the Finnish population. The findings were published in the American Journal of Clinical Nutrition.

Findings from earlier studies addressing the association of dietary cholesterol or egg intake with the risk of stroke have been contradictory...

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More than a Protein Factory: A Role for Ribosomes in regulating human Gene Expression

A new study using human cell lines provides insight on how instructions embedded within mRNA messages can affect mRNA levels, mRNA stability, and protein production in a translation-dependent manner.
Image: Courtesy of Bazzini Lab.

Researchers from the Stowers Institute for Medical Research have discovered a new function of ribosomes in human cells that may show the protein-making particle’s role in destroying healthy mRNAs, the messages that decode DNA into protein.

“For a long time, many people have viewed ribosomes as a passive player in the cell – a molecular machine that’s just producing proteins,” says Stowers Assistant Investigator Ariel Bazzini, PhD. “Now there’s growing evidence that ribosomes regulate gene expression, including in human cells.”

These findings, which were rece...

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How to Enhance or Suppress Memories

This is what a bad memory looks like in a mouse brain. The cells glowing green indicate that they are being activated in storing a fear memory. Credit: The Ramirez Group, Boston University

Stimulating different parts of the brain can dial up or down a specific memory’s emotional oomph, study shows. What if scientists could manipulate your brain so that a traumatic memory lost its emotional power over your psyche? Steve Ramirez, a Boston University neuroscientist fascinated by memory, believes that a small structure in the brain could hold the keys to future therapeutic techniques for treating depression, anxiety, and PTSD, someday allowing clinicians to enhance positive memories or suppress negative ones.

Inside our brains, a cashew-shaped structure called the hippocampus stores t...

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Anxiety might be Alleviated by Regulating Gut Bacteria

Gut microbes illustration.
Credit: © nobeastsofierce / Adobe Stock

Review of studies suggests a potentially useful link between gut bacteria and mental disorders. People who experience anxiety symptoms might be helped by taking steps to regulate the microorganisms in their gut using probiotic and non-probiotic food and supplements, suggests a review of studies published today in the journal General Psychiatry.

Anxiety symptoms are common in people with mental diseases and a variety of physical disorders, especially in disorders that are related to stress. Previous studies have shown that as many as a third of people will be affected by anxiety symptoms during their lifetime.

Increasingly, research has indicated that gut microbiota – the trillions of microorganisms in the gut wh...

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