Category Biology/Biotechnology

Does Insulin Resistance cause Fibromyalgia?


Effect of metformin treatment on pain as measured by the NPRS (0–10 scale).

A newly confirmed link with insulin resistance may radically change the way fibromyalgia and related forms of chronic pain are identified and managed. Researchers led by a team from The University of Texas Medical Branch at Galveston were able to dramatically reduce the pain of fibromyalgia patients with medication that targeted insulin resistance.

This discovery could dramatically alter the way that chronic pain can be identified and managed. Dr. Miguel Pappolla, UTMB professor of neurology, said that although the discovery is very preliminary, it may lead to a revolutionary shift on how fibromyalgia and related forms of chronic pain are treated...

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Pigment-producing Stem cells can Regenerate vital part of Nervous system

“This research holds promise for treating serious neurodegenerative diseases that impact millions of people each year. Our researchers at the University of Maryland School of Medicine have discovered what could be a critical and non-invasive way to use stem cells as a therapy for these diseases,” said UMSOM DeanE. Albert Reece, MD, PhD, MBA, Executive Vice President for Medical Affairs, UM Baltimore, and the John Z. and Akiko K. Bowers Distinguished Professor.

Researchers discover certain skin-related stem cells could help in treating neurogenerative diseases. Neurodegenerative diseases like multiple sclerosis (MS) affect millions of people worldwide and occur when parts of the nervous system lose function over time...

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Embryo Stem Cells created from Skin Cells


Direct Induction of the Three Pre-implantation Blastocyst Cell Types from Fibroblasts

Researchers at the Hebrew University of Jerusalem (HU) have found a way to transform skin cells into the 3 major stem cell types that comprise early-stage embryos. The work (in mouse cells) has significant implications for modelling embryonic disease and placental dysfunctions, as well as paving the way to create whole embryos from skin cells.

As published in Cell Stem Cell, Dr. Yossi Buganim of HU’s Department of Developmental Biology and Cancer Research and his team discovered a set of genes capable of transforming murine skin cells into all three of the cell types that comprise the early embryo: the embryo itself, the placenta and the extra-embryonic tissues, such as the umbilical cord...

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Organ Bioprinting gets a Breath of Fresh Air

Bioprinting research from the lab of Rice University bioengineer Jordan Miller featured a visually stunning proof-of-principle — a scale-model of a lung-mimicking air sac with airways and blood vessels that never touch yet still provide oxygen to red blood cells.
Credit: Photo by Jordan Miller/Rice University

Bioengineers clear major hurdle on path to 3D printing replacement organs. Bioengineers have cleared a major hurdle on the path to 3D printing replacement organs with a breakthrough technique for bioprinting tissues. The new innovation allows scientists to create exquisitely entangled vascular networks that mimic the body’s natural passageways for blood, air, lymph and other vital fluids.

The research is featured on the cover of this week’s issue of Science...

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