Category Biology/Biotechnology

3D-printed Prosthetic Implants could improve Treatment for Hearing Loss

This is a size comparison between 3-D printed prosthesis implant and a penny. Credit: Radiological Society of North America

This is a size comparison between 3-D printed prosthesis implant and a penny. Credit: Radiological Society of North America

Researchers using CT scans and 3D printing have created accurate, custom-designed prosthetic replacements for damaged parts of the middle ear, according to a study being presented today at the annual meeting of the Radiological Society of North America (RSNA). The technique has the potential to improve a surgical procedure that often fails because of incorrectly sized prosthetic implants, researchers said. Hearing works partly through the transmission of vibrations from the ear drum to the cochlea, the sensory organ of hearing, via 3 tiny bones in the middle ear known as ossicles...

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Fighting Myocardial Infarction with Nanoparticle Tandems

Via a cannula introduced into the infarction area, the cells loaded with magnetic nanoparticles are injected into the damaged heart muscle tissue of the mouse. Credit: Copyrighted Photo: Dr. Annika Ottersbach/Uni Bonn

Via a cannula introduced into the infarction area, the cells loaded with magnetic nanoparticles are injected into the damaged heart muscle tissue of the mouse. Credit: Copyrighted Photo: Dr. Annika Ottersbach/Uni Bonn

Researchers show in mice that transplanted muscle cells display improved engraftment in a magnetic field How can damaged cardiac tissue following a heart attack best be treated with replacement muscle cells? A team under the supervision of the University of Bonn is now presenting an innovative method on mice: Muscle replacement cells, which are to take over the function of the damaged tissue, are loaded with magnetic nanoparticles...

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3D-printed Minifactories

3D printing with a new kind of ink which is containing living bacteria. (Illustration: science animated by Bara Krautz)

3D printing with a new kind of ink which is containing living bacteria. (Illustration: science animated by Bara Krautz)

A group of ETH researchers has now introduced a new 3D printing platform that works using living matter. The researchers developed a bacteria-containing ink that makes it possible to print mini biochemical factories with certain properties, depending on which species of bacteria the scientists put in the ink. They used Pseudomonas putida and Acetobacter xylinum in their work. The former can break down the toxic chemical phenol, which is produced on a grand scale in the chemical industry, while the latter secretes high-purity nanocellulose. This bacterial cellulose relieves pain, retains moisture and is stable, opening up potential applications in the treatment of burns...

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Targeted Treatment could prevent spread of Pancreatic cancer, Heart Damage

Pancreatic cancer cells, under a microscope. Credit: University of Cincinnati

Pancreatic cancer cells, under a microscope. Credit: University of Cincinnati

Researchers at the University of Cincinnati (UC) College of Medicine have shown that a new targeted treatment could benefit patients with certain pancreatic tumors by preventing spread of the cancer and protecting their heart from damage – a direct result of the tumor. Higher levels of serotonin among other tumor secretions can cause injury to the valves of the heart over time, leading to cardiac impairment – a condition referred to as cardiac carcinoid disease – in these patients.

These findings, reported in the November 2017 issue of Molecular Cancer Therapeutics, could lead to another targeted treatment for patients and prevent the onset of additional complications from their cancer...

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