Category Biology/Biotechnology

Lumbar spine MRI showing vertebra at baseline and three months after treatment. Credit: Radiological Society of North America

The majority of patients were pain free after receiving a new image-guided pulsed radiofrequency treatment for low back pain and sciatica, according to a study presented today at the annual meeting of the Radiological Society of North America (RSNA). Low back pain is an extremely common problem that affects at least 80% of the population at some point in their lifetime. It is the most common cause of job-related disability. Low back pain affects men and women equally.

Most back pain is short-term, but about 20% of people affected by acute low back pain go on to develop chronic low back pain lasting a year or more...

Clusters of B (red) and T (green) lymphocytes in pericardial adipose tissue. Fat-laden cells and connective tissue are stained blue. (Mariaelvy Bianchini; Michael Horckmans/LMU)

The damage caused by a heart attack triggers an inflammatory reaction which degrades the affected tissue. This response is orchestrated by immune cells that reside in the nearby pericardial adipose tissue, as a study by a team of Ludwig-Maximilians-Universitaet (LMU) in Munich shows. Following a heart attack, the innate immune system must kick in fast in order to limit the damage and stimulate tissue repair...

Jayakrishna Ambati, M.D., (left) and Nagaraj Kerur, Ph.D., have discovered a crucial trigger for macular degeneration, a condition which robs millions of their sight. The discovery may allow doctors to intervene early to halt the process. Credit: Josh Barney | UVA Health System

Unexpected finding points to potential way to stop macular degeneration. Researchers at the University of Virginia School of Medicine have discovered a critical trigger for the damaging inflammation that ultimately robs millions of their sight. The finding may allow doctors to halt the inflammation early on, potentially saving patients from blindness. “Almost 200 million people in the world have macular degeneration...

Illinois researchers developed nanoparticles that can target cancer stem cells (yellow), the rare cells within a tumor (blue) that can cause cancer to recur or spread. Credit: Image courtesy of Dipanjan Pan

University of Illinois researchers are sending tiny drug-laden nanoparticles on a mission to seek and destroy cancer stem cells, the elusive and rare cells that can cause cancer to come back even when years have passed since the initial tumor was treated. In a study led by Dipanjan Pan, an Illinois professor of bioengineering, researchers designed nanoparticles that specifically bind to a protein that marks the surface of breast cancer stem cells...