Category Health/Medical

Over the past decade, researchers have made great strides in the development and administration of cancer immunotherapies, which use the body’s own immune system to treat disease. However, the therapies don’t work for every person or with every type of cancer, and gaps in our understanding of exactly how the body mounts an anti-cancer immune response has slowed progress toward making them universally effective.

In a new study, researchers at the University of Chicago Medicine Comprehensive Cancer Center and the University of Amsterdam have brought insight into one crucial step in the anti-cancer immune response process: T cell priming.

Previous studies implied that a single mechanism—antigen cross presentation—is responsible for priming T cells, the immune system’s disease fight...

Scientists have demonstrated that normal brain aging is accelerated by approximately 26% in people with progressive type 2 diabetes compared with individuals without the disease, reports a study published today in eLife.

The authors evaluated the relationship between typical brain aging and that seen in type 2 diabetes, and observed that type 2 diabetes follows a similar pattern of neurodegeneration as aging, but which progresses faster. One important implication of this finding is that even typical brain aging may reflect changes in the brain’s regulation of glucose by insulin.

The results further suggest that by the time type 2 diabetes is formally diagnosed, the...

For the first time TU Graz’s Institute of Theoretical Computer Science and Intel Labs demonstrated experimentally that a large neural network can process sequences such as sentences while consuming 4X – 16X less energy while running on neuromorphic hardware than non-neuromorphic hardware. The new research based on Intel Labs’ Loihi neuromorphic research chip that draws on insights from neuroscience to create chips that function similar to those in the biological brain.

The research was funded by The Human Brain Project (HBP), one of the largest research projects in the world with more than 500 scientists and engineers across Europe studying the human bra...

The cornea—the transparent protective outer layer of the eye critical to helping us see—produces a delicate and limited immune response to fight infections without damaging our vision, according to a new study from the Peter Doherty Institute for Infection and Immunity (Doherty Institute).

Published today in Cell Reports, the study has shown long-living memory T cells that patrol and fight viral infections are present in the cornea, upending current thought that T cells are not found in healthy corneas—expanding our understanding of the eye’s immune response to infections.

The team used a multiphoton microscope that provides live images of living, intact biological tissues to study cornea cells in mice infected with Herpes Simplex Virus.

Their images revealed long-livin...