Category Health/Medical

Scientists identify Gut-derived Metabolites that play a role in Neurodegeneration

A new study has identified gut-derived metabolites that appear to be neurotoxic and play a role in the progression of multiple sclerosis. Credit: Nicoletta Barolini

A New York-based, multi-institutional research team has found high levels of three toxic metabolites produced by gut bacteria in the cerebrospinal fluid and plasma samples of multiple sclerosis (MS) patients. The important findings, published in the journal Brain, further scientists’ understanding of how gut bacteria can impact the course of neurological diseases by producing compounds that are toxic to nerve cells.

Previously published evidence has supported the concept that an imbalance in the gut microbiota—the community of organisms that live in the human intestines—may underly a range of neurological disorders...

Read More

Soft Semiconductors that Stretch Like Human Skin Can Detect UltraLow Light Levels

Three engineering labs at Georgia Tech collaborated to demonstrate a new level of stretchability of a photodetector. Pictured above is first author Youngrak Park (right) with the lab leads (L to R) Bernard Kippelen,  Samuel Graham, and Olivier Pierron. (Photo credit: Ben Wright, Georgia Tech)

Flexible electronics breakthrough could enhance biosensor technology, from wearables to soft-robotic implantable systems. Semiconductors are moving away from rigid substrates, which are cut or formed into thin discs or wafers, to more flexible plastic material and even paper thanks to new material and fabrication discoveries. The trend toward more flexible substrates has led to fabrication of numerous devices, from light-emitting diodes to solar cells and transistors.

Georgia Tech researchers h...

Read More

Breakthrough Infections generate ‘Super Immunity’ to COVID-19, study suggests

Daniel Streblow, Ph.D., holds a plate of plasma samples that contain COVID-19 antibodies, to be evaluated in OHSUs in-house COVID-19 testing lab. Researchers have been studying antibody testing approaches. (OHSU/Kristyna Wentz-Graff)

Breakthrough infections greatly enhance immune response to variants of the virus that causes COVID-19, according to a newly published study from Oregon Health & Science University.

The laboratory results, published online ahead of print today in the Journal of the American Medical Association (JAMA), reveal that a breakthrough infection generates a robust immune response against the delta variant. Authors say the findings suggest the immune response is likely to be highly effective against other variants as the SARS-CoV-2 virus continues to mutate.

T...

Read More

Gallic Acid and Stretching Decrease Osteoarthritis Markers in Cartilage Cells

Image by Manuel Gonzalez Reyes on Pixabay

A healthy diet and a little exercise appear to be good for arthritis, even on the cellular level. A team led by Washington State University researchers used gallic acid, an antioxidant found in gallnuts, green tea and other plants, and applied a stretching mechanism to human cartilage cells taken from arthritic knees that mimics the stretching that occurs when walking. The combination not only decreased arthritis inflammation markers in the cells but improved the production of desired proteins normally found in healthy cartilage.

While still at an early stage, the findings suggest a new procedure could be developed to treat cartilage cells extracted from a patient to grow a supply of cells or a tissue to be re-implanted.

“We found the com...

Read More