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    Category Health/Medical

    Scientists reveal the Mechanism of Skeletal Muscle Stem Cell Activation in Muscle Regeneration

    February 25, 2022, Categories  Health/Medical, Biology/Biotechnology

    Discordant proteomic and transcriptomic signatures reveal a potential translational control mechanism during the SC quiescence-to-activation transition. a Schematic illustration of the workflow for the proteomic analysis of FACS-isolated SCs. The SCs were sorted from Pax7-nGFP mice. QSCs were sorted from 0.5% PFA-perfused mice. fiSCs were sorted from unperfused mice. Injured ASCs (iASCs) were sorted from 3 days 1.2% BaCl2 injured mice. Cultured ASCs (cASCs) were 2 days cultured SCs. (n = 2 independent experiments). b Hierarchical clustering of the protein expression (in the number of spectra) for QSCs, fiSCs, iASCs, and cASCs. c Heatmap of representative expression for cell cycle, quiescence, and activation-specific proteins of QSCs, fiSCs, iASCs, and cASCs...
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    More Sensitive X-ray Imaging

    February 25, 2022, Categories  Physics, Health/Medical

    Researchers at MIT have shown how one could improve the efficiency of scintillators by at least tenfold by changing the material’s surface. This image shows a TEM grid on scotch tape, with the right side showing the scene after it is corrected.
    Credits:Image: Courtesy of the researchers, edited by MIT New

    Improvements in the material that converts X-rays into light, for medical or industrial images, could allow a tenfold signal enhancement.

    Scintillators are materials that emit light when bombarded with high-energy particles or X-rays. In medical or dental X-ray systems, they convert incoming X-ray radiation into visible light that can then be captured using film or photosensors...

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    A Type of Virus present in the Gut Microbiota is Associated with Better Cognitive Ability in Humans, Mice and Flies

    February 24, 2022, Categories  Biology/Biotechnology, Health/Medical

    Study finds a greater presence of these viruses in people who eat dairy products in their regular diet. New research associates the presence of Caudovirales in gut microbiota to an improvement in cognitive functions and memory in humans, mice and flies. The article, published in the journal Cell Host & Microbe, was led by Dr. Jordi Mayneris-Perxachs and Dr. José Manuel Fernández-Real, of the Nutrition, Eumetabolism and Health group of the Girona Biomedical Research Institute (IDIBGI) Dr. Josep Trueta and CIBEROBN, and has been carried out in collaboration with the Neuropharmacology research group led by Dr...

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    Connecting Science to Medicine: Tendon-like Tissue created from Human Stem Cells

    February 23, 2022, Categories  Health/Medical, Biology/Biotechnology

    Researchers develop artificial tendons in vitro from human stem cells that could fix common tendon injuries such as Achilles tendon rupture. Tendons are tissues that connect muscles to bones and are important for movement and locomotion. Injuries to tendons are quite common, with millions of people — particularly athletes — affected worldwide, and can often take many months to recover from, significantly impacting quality of life. Furthermore, while many options for treatment exist, none of them are perfect cures and many result in pain, immunogenicity, or long-term treatment failure. Therefore, a novel therapeutic strategy for tendon repair is needed.

    In a study published in the Journal of Tissue Engineering in January 2022, researchers from Tokyo Medical and Dental University (TM...

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