Category Health/Medical

Gallic Acid and Stretching Decrease Osteoarthritis Markers in Cartilage Cells

Image by Manuel Gonzalez Reyes on Pixabay

A healthy diet and a little exercise appear to be good for arthritis, even on the cellular level. A team led by Washington State University researchers used gallic acid, an antioxidant found in gallnuts, green tea and other plants, and applied a stretching mechanism to human cartilage cells taken from arthritic knees that mimics the stretching that occurs when walking. The combination not only decreased arthritis inflammation markers in the cells but improved the production of desired proteins normally found in healthy cartilage.

While still at an early stage, the findings suggest a new procedure could be developed to treat cartilage cells extracted from a patient to grow a supply of cells or a tissue to be re-implanted.

“We found the com...

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Uncovered: Key to how Exercise Protects against Consequences of Ageing

Staining showing mitochondria within individual muscle fibres. Credit: Monash University

Monash University, Australia scientists have discovered an enzyme that is key to why exercise improves our health. Importantly this discovery has opened up the possibility of drugs to promote this enzyme’s activity, protecting against the consequences of aging on metabolic health, including type 2 diabetes.

The proportion of people worldwide over 60 years old will double in the next three decades and by 2031, more than six million Australians will be over 65 years old. The incidence of type 2 diabetes increases with age so this aging population will also result in an increased incidence of the disease globally.

One of the main reasons for the increased prevalence of type 2 diabetes with age i...

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For Children, Young Adults with Recurrent AML, Immunotherapy Shows Promise

GARA ELIZABETH PHOTOGRAPHYResearchers at Washington University School of Medicine in St. Louis have shown, in a small clinical trial, that pre-activated natural killer cells can help some children and young adults with recurrent AML and few other treatment options. Pictured is Weston Robinett, 3, a patient who received this investigational therapy at Siteman Kids at St. Louis Children’s Hospital and Washington University School of Medicine. He remains in remission more than two years after treatment.

Natural killer cells could help young patients with few treatment options. An immunotherapy harnessing the immune system’s “natural killer” cells has proven effective in treating acute myeloid leukemia (AML) in some adults whose cancers return...

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How Organic Neuromorphic Electronics Can Think and Act

A combination of organic materials and electronics could open up new possibilities for unconventional future computing systems. The processor is the brain of a computer — an often-quoted phrase. But processors work fundamentally differently than the human brain. Transistors perform logic operations by means of electronic signals. In contrast, the brain works with neurons, which are connected via biological conductive paths, synapses. At a higher level, this signaling is used by the brain to control the body and perceive the surrounding environment. The reaction of the body/brain system when certain stimuli are perceived — for example, via the eyes, ears or sense of touch — is triggered through a learning process...

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