Category Health/Medical

The New Pill can Inject Large Quantities of Monoclonal Antibodies and other drugs into the Lining of the Stomach after being Swallowed.

diagram of antibodies entering stomach
Caption:The new pill can inject large quantities of monoclonal antibodies and other drugs into the lining of the stomach after being swallowed.
Credits:Image: courtesy of the researchers

In recent years, scientists have developed monoclonal antibodies — proteins that mimic the body’s own immune defenses — that can combat a variety of diseases, including some cancers and autoimmune disorders such as Crohn’s disease. While these drugs work well, one drawback to them is that they have to be injected.

A team of MIT engineers, in collaboration with scientists from Brigham and Women’s Hospital and Novo Nordisk, is working on an alternative delivery strategy that could make it much easier for patients to benefit from monoclonal antibodies and other drugs that usually have to be injected...

Read More

Novel assessment of Platelet-Rich Plasma Treatment shows Efficacy in Patients with Osteoarthritis

Knee joint pain

A pilot study conducted by researchers at Baylor College of Medicine combined wearable technology and patient-reported outcomes to assess the efficacy of platelet-rich plasma (PRP) treatment in osteoarthritis (OA).

The results, published in the journal Regenerative Medicine, showed that a single injection of leukocyte-rich/PRP in the knee joint significantly improved functional mobility, pain and quality of life after six weeks. The study supports using this combined approach to further evaluate this and other emerging biological therapies for musculoskeletal disorders in larger clinical trials.

“OA is a leading cause of disabilities, affecting nearly 52 million Americans,” said first and corresponding author Dr...

Read More

‘Charging room’ system powers Lights, Phones, Laptops Without Wires

The finished charging room, located at The University of Tokyo. Image credit: The University of Tokyo

In a move that could one day free the world’s countertops from their snarl of charging cords, researchers at the University of Michigan and University of Tokyo have developed a system to safely deliver electricity over the air, potentially turning entire buildings into wireless charging zones.

Detailed in a new study published in Nature Electronics, the technology can deliver 50 watts of power using magnetic fields.

Study author Alanson Sample, U-M professor of computer science and engineering, says that in addition to untethering phones and laptops, the technology could also power implanted medical devices and open new possibilities for mobile robotics in homes and manufacturing...

Read More

Cytokine APRIL Protects from Atherosclerotic Cardiovascular disease

Heart attacks and strokes are the main causes of death and loss of productive years globally. These clinical complications are caused by atherosclerosis, which is a chronic disease that leads to the accumulation of LDL cholesterol and immune cells in the inner layer of arteries and thereby resulting in the build-up of atherosclerotic plaques. Researchers from the Department of Laboratory Medicine of the Medical University of Vienna in collaboration with colleagues from the University of Lausanne (Switzerland) and the University of Cambridge (UK) have identified that a cytokine called A Proliferation Inducing Ligand (APRIL) plays a major protective role against the formation of atherosclerotic plaques. The study was now published in the journal Nature.

The investigators found that g...

Read More