Category Health/Medical

Researchers at Touro University Nevada have discovered that tiny particles in the blood, called extracellular vesicles (EVs), are a major player in how a group of hormones are shuttled through the body. Physical exercise can stimulate this process.

The findings, published in the journal Proceedings of the National Academy of Sciences, open the door to deeper understanding of hormone circulation and access to the brain, how exercise may trigger changes in energy balance, mental health, and immune function, and circulation of certain drugs.

Blood and other body fluids are teeming with EVs—tiny particles that exist outside of cells...

Theobromine is found in cocoa and, to a lesser extent, coffee. It is chemically similar to caffeine but does not have such a pronounced stimulant effect.

A new study, published in the journal Aging, measured levels of this compound in people’s blood.

They found that those with the highest levels had epigenetic markers associated with slower biological aging.

But what is theobromine?
Theobromine is a bioactive phytochemical, meaning that it comes from a plant, and it can influence human physiology.

The primary sources of theobromine in the human diet are chocolate and, to a lesser extent, coffee.

This compound is a major component of cocoa beans, comprising around 3.3% by weight. It is molecularly similar to caffeine and shares some of its effects.

However, experts c...

A study by researchers at the Federal University of São Carlos (UFSCar) in Brazil, in partnership with University College London (UCL) in the United Kingdom, concluded that the combination of abdominal fat and muscle loss increases the risk of death by 83%, compared to people without these conditions.

This combination is so dangerous that it identifies an even greater problem: sarcopenic obesity. This condition is characterized by loss of muscle mass while gaining fat throughout the body. It is a difficult condition to diagnose, and it is related to loss of autonomy and a worsening quality of life in older adults...

Heart muscle cells grown from patient stem cells—known as human induced pluripotent stem cell–derived cardiomyocytes, or hiPSC-CMs—are a promising way to repair hearts damaged by heart attacks and heart failure. But transplanted hiPSC-CMs often have trouble syncing to the rhythm of native heart cells, which can cause dangerous arrhythmias after transplantation.

Efforts to improve cell integration
For years, stem cell biologists and cardiac researchers have been looking for ways to improve how implanted hiPSC-CMs mature and integrate into the heart. The challenge is that once the hiPSC-CMs are implanted in vivo, it’s hard to monitor how they integrate.

Now, Harvard University researchers have developed the first platform capable of continuously monitoring how transplanted ce...