Category Health/Medical

Binary Stars are all around us, new Map of Solar neighborhood shows

A colorful collage of binary star pairs near Earth, courtesy of the Gaia survey.

Gaia survey provides location and motion of 1.3 million binary pairs within 3,000 light years of Earth. A doctoral student has mined the most recent Gaia survey for all binary stars near Earth and created a 3D atlas of 1.3 million of them. The last local survey included about 200 binary pairs. With such census data, astronomers can conduct statistical analyses on binary populations. For pairs that contain white dwarfs, it’s possible to determine the age of their main-sequence companion, and thus of any exoplanets around them.

The latest star data from the Gaia space observatory has for the first time allowed astronomers to generate a massive 3D atlas of widely separated binary stars within about 3,000 l...

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How a Longevity Gene protects Brain Stem Cells from Stress

cells under a microscope
Antioxidant treatment boosts the birth of new neurons from stem cells by suppressing stress signaling. Image courtesy of the Paik lab.

A gene linked to unusually long lifespans in humans protects brain stem cells from the harmful effects of stress, according to a new study by Weill Cornell Medicine investigators.

Studies of humans who live longer than 100 years have shown that many share an unusual version of a gene called Forkhead box protein O3 (FOXO3). That discovery led Dr. Jihye Paik, associate professor of pathology and laboratory medicine at Weill Cornell Medicine, and her colleagues to investigate how this gene contributes to brain health during aging.

In 2018, Dr...

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New Potential Therapy for Crohn’s disease in Children

High magnification micrograph of Crohn’s disease. Biopsy of esophagus. H&E stain. Credit: Nephron/Wikipedia

Scientists from the Stanley Manne Children’s Research Institute at Ann & Robert H. Lurie Children’s Hospital of Chicago demonstrated that a nanotherapy reduces intestinal inflammation and shrinks lesions in a rodent model of severe Crohn’s disease. This approach could become an alternative to biologic antibody therapies that carry many side effects, including increased risk of certain cancers. It might also prevent the need for surgery in the future. Findings were published in the journal Advanced Therapeutics.

Crohn’s disease is an inflammatory bowel disease characterized by chronic inflammation of the digestive tract, most often in the small intestine...

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Gut Microbiome implicated in Healthy Aging and Longevity

gut
Credit: CC0 Public Domain

Data from over 9,000 people reveal a distinct gut microbiome signature that is associated with healthy aging and survival in the latest decades of life. The gut microbiome is an integral component of the body, but its importance in the human aging process is unclear. ISB researchers and their collaborators have identified distinct signatures in the gut microbiome that are associated with either healthy or unhealthy aging trajectories, which in turn predict survival in a population of older individuals. The work is set to be published in the journal Nature Metabolism.

The research team analyzed gut microbiome, phenotypic and clinical data from over 9,000 people — between the ages of 18 and 101 years old — across three independent cohorts...

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