Category Health/Medical

Your gut microbes can be anti-aging—scientists are uncovering how to keep your microbiome youthful

People have long given up on the search for the Fountain of Youth, a mythical spring that could reverse aging. But for some scientists, the hunt has not ended—it’s just moved to a different place. These modern-day Ponce de Leóns are investigating whether gut microbes hold the secret to aging well.

The gut microbiome refers to the vast collection of microscopic organisms—bacteria, fungi, and viruses—that largely inhabit the colon. These microbes aid in digestion and produce molecules that affect your physiology and psychology. The composition of the microbiome is influenced by a combination of factors, including genetics, diet, the environment, medications, and age.

I’m a microbiology professor and author of “Pleased to Meet Me: Genes, Germs and the Curious Forces That Mak...

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Closing in on a universal vaccine: Nasal spray protects mice from respiratory viruses, bacteria and allergens

Pulendran-universal-vax-square
Stanford Medicine researchers have developed an intranasal vaccine that protects mice against respiratory viruses, bacteria and allergens.
Chinamon/Adobe Stock

In the realm of medical advancements, a universal vaccine that can protect against any pathogen has long been a Holy Grail—and about as elusive as a mythological vessel. But Stanford Medicine researchers and collaborators have taken an astonishing step forward in that quest, surprising even themselves.

In a new study in mice, they have developed a universal vaccine formula that protects against a wide range of respiratory viruses, bacteria and even allergens. The vaccine is delivered intranasally—such as through a nasal spray—and provides broad protection in the lungs for several months.

In the study, published in Sci...

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Scientists find a mechanism showing how exercise protects the brain

Scientists find a mechanism for how exercise protects the brain
Credit: Cell (2026). DOI: 10.1016/j.cell.2026.01.024

Researchers at UC San Francisco have discovered a mechanism that could explain how exercise improves cognition by shoring up the brain’s protective barrier. With age, the network of blood vessels—called the blood–brain barrier—gets leaky, letting harmful compounds enter the brain. This causes inflammation, which is associated with cognitive decline and is seen in conditions like Alzheimer’s disease. The research is published in the journal Cell.

Six years ago, the team identified a brain-rejuvenating enzyme called GPLD1 that mice produced in their livers when they exercised. But they couldn’t understand how it worked, because it cannot get into the brain.

The new study answers that question...

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This new blood test could detect cancer before it shows up on scans

Caption: When the biomarker is detected, the Cas12a protein used for CRISPR cuts the DNA holding the quantum dots, which causes a measurable drop in SHG signal.
Credit: Han Zhang, Shenzhen University

A new CRISPR-powered light sensor can detect the faintest molecular signs of cancer in a drop of blood. A new light-based sensor can spot incredibly tiny amounts of cancer biomarkers in blood, raising the possibility of earlier and simpler cancer detection. The technology merges DNAnanotechnology, CRISPR, and quantumdots to generate a clear signal from just a few molecules. In lung cancer tests, it worked even in real patient serum samples. Researchers hope it could eventually power portable blood tests for cancer and other diseases.

Scientists have designed a powerful light based sensor...

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