Category Health/Medical

We know that the vaccines now available across the world will protect their recipients from getting sick with Covid-19. But while each vaccine authorized for public use can prevent well over 50% of cases (in Pfizer-BioNTech and Moderna‘s case, more than 90%), what we don’t know is whether they’ll also curb transmission of the SARS-CoV-2 virus.

That question is answerable, though—and understanding vaccines’ effect on transmission will help determine when things can go back to whatever our new normal looks like.

The reason we don’t know if the vaccine can prevent transmission is twofold. One reason is practical...

Antiviral protein MDA-5 senses viral replication and governs immune response to SARS-CoV-2. Scientists at Sanford Burnham Prebys Medical Discovery Institute have identified the sensor in human lungs that detects SARS-CoV-2 and signals that it’s time to mount an antiviral response. The study, published today in Cell Reports, provides insights into the molecular basis of severe disease and may enable new strategies for the treatment and prevention of COVID-19.

“Our research has shown that MDA-5 is the immune cop that’s tasked to keep an eye out for SARS-CoV-2 and call for back-up,” says Sumit Chanda, Ph.D., director of the Immunity and Pathogenesis Program at Sanford Burnham Prebys and senior author of the study...

Treatment reverses paralysis in mice; offers a general delivery platform for neurologic drugs. Currently there’s no treatment for botulism once the toxin gets into neurons...

Engineers demonstrate a new shape-changing nozzle that could revolutionize ‘4D printing’ applications. Engineers at the University of Maryland (UMD) have created a new shape-changing or “morphing” 3D printing nozzle that was featured as a Frontispiece in the January 5th issue of the journal Advanced Materials Technologies.

The team’s morphing nozzle offers researchers new means for 3D printing “fiber-filled composites” — materials made up of short fibers that boost special properties over traditional 3D-printed parts, such as enhancing part strength or electrical conductivity. The challenge is that these properties are based on the directions or “orientations” of the short fibers, which has been difficult to control during the 3D printing process, until now.

“When 3D printing wi...