Category Health/Medical

How Exercise Stalls Cancer Growth through the Immune System

Woman adjusting her shoelaces before training.

People with cancer who exercise generally have a better prognosis than inactive patients. Now, researchers at Karolinska Institutet in Sweden have found a likely explanation of why exercise helps slow down cancer growth in mice: Physical activity changes the metabolism of the immune system’s cytotoxic T cells and thereby improves their ability to attack cancer cells. The study is published in the journal eLife.

“The biology behind the positive effects of exercise can provide new insights into how the body maintains health as well as help us design and improve treatments against cancer,” says Randall Johnson, professor at the Department of Cell and Molecular Biology, Karolinska Institutet, and the study’s corresponding author.

Prior research has shown that physical activity can p...

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Aspirin use Reduces Risk of Death in hospitalized COVID-19 patients

University of Maryland School of Medicine
Jonathan H. Chow , et al. Aspirin Use is Associated with Decreased Mechanical Ventilation, ICU Admission, and In-Hospital Mortality in Hospitalized Patients with COVID-19Anesthesia & Analgesia, 2020; Publish Ahead of Print DOI: 10.1213/ANE.0000000000005292

Hospitalized COVID-19 patients who were taking a daily low-dose aspirin to protect against cardiovascular disease had a significantly lower risk of complications and death compared to those who were not taking aspirin, according to a new study led by researchers at the University of Maryland School of Medicine (UMSOM)...

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Bacterial Metabolism of Dietary Soy may Lower Risk Factor for Dementia

S-Equol - an overview | ScienceDirect Topics

A metabolite produced following consumption of dietary soy may decrease a key risk factor for dementia — with the help of the right bacteria, according to a new discovery led by researchers at the University of Pittsburgh Graduate School of Public Health.

Their study, published today in the journal Alzheimer’s & Dementia: Translational Research & Clinical Interventions, reports that elderly Japanese men and women who produce equol — a metabolite of dietary soy created by certain types of gut bacteria — display lower levels of white matter lesions within the brain.

“White matter lesions are significant risk factors for cognitive decline, dementia and all-cause mortality,” said lead author Akira Sekikawa, M.D., Ph.D., associate professor of epidemiology at Pitt Public Health...

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Observed COVID-19 Variability may have underlying molecular sources

Understand variability of COVID-19 through population and tissue variations in expression of SARS-CoV-2 host genes
Author links open overlay panel LiangChena
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Study shows how variations in SARS-CoV-2 host gene expression can be linked to variations in COVID-19 susceptibility and symptom severity. People have different susceptibilities to SARS-CoV-2, the virus behind the COVID-19 pandemic, and develop varying degrees of fever, fatigue, and breathing problems — common symptoms of the illness. What might explain this variation?

Scientists at the University of California, Riverside, and University of Southern California may have an answer to this mystery.

In a paper published in Informatics in Medicine Unlocked, the researchers show for the first time that the observed COVID-19 vari...

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