Category Health/Medical

Strong Activation of Anti-bacterial T cells linked to Severe COVID-19

Illustration of T cells fighting virus
Illustration: Getty Im“MAIT cell activation and dynamics associated with COVID-19 disease severity,” Parrot, T., Gorin, J. B., Ponzetta, A., Maleki, K. T., Kammann, T., Emgård, J., Perez-Potti, A., Sekine, T., Rivera-Ballesteros, O., the Karolinska COVID-19 Study Group, Gredmark-Russ, S., Rooyackers, O., Folkesson, E., Eriksson, L. I., Norrby-Teglund, A., Ljunggren, H. G., Björkström, N. K., Aleman, S., Buggert, M., Klingström, J., Strålin, K., and Sandberg, J. K., Science Immunology, online 28 september, 2020, doi: 10.1126/sciimmunol.abe1670ages

A type of anti-bacterial T cells, so-called MAIT cells, are strongly activated in people with moderate to severe COVID-19 disease, according to a study by researchers at Karolinska Institutet in Sweden that is published in the journal...

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First Evidence that Air Pollution Particles and Metals are Reaching the Placenta

Black inclusions in placental cells resembling inhaled particulate matter

Pollution particles, including metals, have been found in the placentas of fifteen women in London, according to research led by Queen Mary University of London.

The study, funded by Barts Charity and published in the journal Science of The Total Environment, demonstrate that inhaled particulate matter from air pollution can move from the lungs to distant organs, and that it is taken up by certain cells in the human placenta, and potentially the fetus.

The researchers say that further research is needed to fully define the direct effect that pollution particles may have on the developing fetus.

Lead author Professor Jonathan Grigg from Queen Mary University of London said: “Our study for the first time shows that ...

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Uncovering a ‘suPAR’ culprit behind Kidney Injury in COVID-19

drawing of kidneys on lined paper

Kidney injury is a dreaded complication in patients hospitalized for COVID-19, with more than a third of patients ending up in need of dialysis. Patients with COVID-19-related kidney injury are also at much higher risk of death.

“We don’t known exactly why patients with severe COVID-19 have a high rate of kidney injury,” says Salim Hayek, M.D., a cardiologist at the Michigan Medicine (University of Michigan) Frankel Cardiovascular Center and senior author of a new observational study.” It is, however, becoming clearer that a hyperactive immune system plays a major role in the morbidity of COVID-19, including kidney-related complications.”

In the multi-center study published in the Journal of the American Society of Nephrology, Hayek and an international team of experts report th...

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Researchers have built a new device that acts just like a brain cell. | Image: Ella Maru Studio

These systems could potentially overcome computational hurdles faced by current digital technologies. In the September issue of the journal Nature, scientists from Texas A&M University, Hewlett Packard Labs and Stanford University have described a new nanodevice that acts almost identically to a brain cell. Furthermore, they have shown that these synthetic brain cells can be joined together to form intricate networks that can then solve problems in a brain-like manner.

“This is the first study where we have been able to emulate a neuron with just a single nanoscale device, which would otherwise need hundreds of transistors,” said Dr. R...

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