Category Health/Medical

Renewed Hope for Treatment of Pain and Depression

Fig. 3
SAR analysis of adrenorphin variants on ACKR3 and classical opioid receptors.

Novel molecule targets a newly discovered opioid receptor with atypical properties and holds promise for alternative therapeutic strategies.

Researchers at the Department of Infection and Immunity of the Luxembourg Institute of Health (LIH) developed LIH383, a novel molecule that binds to and blocks a previously unknown opioid receptor in the brain, thereby modulating the levels of opioid peptides produced in the central nervous system (CNS) and potentiating their natural painkilling and antidepressant properties...

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Sedentary Behavior Independently predicts Cancer Mortality

Replacing sitting time with 30 minutes of activity associated with lower risk of cancer death. In the first study to look at objective measures of sedentary behavior and cancer mortality, researchers from The University of Texas MD Anderson Cancer Center found that greater inactivity was independently associated with a higher risk of dying from cancer. The most sedentary individuals had an 82% higher risk of cancer mortality compared to the least sedentary individuals. An accelerometer was used to measure physical activity, rather than relying on participants to self-report their activity levels

“This is the first study that definitively shows a strong association between not moving and cancer death,” said Susan Gilchrist, M.D...

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Graphene Smart Textiles developed for Heat Adaptive Clothing

Graphene Smart Textiles The University of Manchester
Using electro-optical tunability of graphene, adaptive optical textiles were made with electrically controlled reflectivity and emissivity covering the infrared and near-infrared wavelengths.

New research on the two-dimensional (2D) material graphene has allowed researchers to create smart adaptive clothing which can lower the body temperature of the wearer in hot climates.

A team of scientists from The University of Manchester’s National Graphene Institute have created a prototype garment to demonstrate dynamic thermal radiation control within a piece of clothing by utilising the remarkable thermal properties and flexibility of graphene. The development also opens the door to new applications such as, interactive infrared displays and covert infrared communication on textile.

T...

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Light-activated ‘CRISPR’ Triggers Precision Gene Editing and Super-fast DNA Repair

In a time-lapse video over eight hours, a high-powered microscope captures the moment when the CRISPR-Cas9 complex cuts two copies of a gene (red glow in blue circle and purple square) in a living cell. Scale Bar: 5 µm. Credit: Yang Liu, Johns Hopkins Medicine

In a series of experiments using human cancer cell lines, scientists at Johns Hopkins Medicine say they have successfully used light as a trigger to make precise cuts in genomic material rapidly, using a molecular scalpel known as CRISPR, and observe how specialized cell proteins repair the exact spot where the gene was cut.

Results of the experiments, published June 11 in Science, not only reveal new details about the DNA repair process, but also are likely, the researchers say, to speed up and aid understanding of the DNA a...

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