Category Health/Medical

Researchers achieve Remote Control of Hormone Release

MIT engineers have developed magnetic nanoparticles (shown in white squares) that can stimulate the adrenal gland to produce stress hormones such as adrenaline and cortisol.
Image: Courtesy of the researchers

Abnormal levels of stress hormones such as adrenaline and cortisol are linked to a variety of mental health disorders, including depression and posttraumatic stress disorder (PTSD). MIT researchers have now devised a way to remotely control the release of these hormones from the adrenal gland, using magnetic nanoparticles.

This approach could help scientists to learn more about how hormone release influences mental health, and could eventually offer a new way to treat hormone-linked disorders, the researchers say...

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Researchers Repurpose Classic Chemotherapy Drug to Overcome Cancer Therapy Resistance

Anticancer immunity targeting therapy-resistant leukemia stem cells is activated by low-dose doxorubicin.
Image/Art credit: Mark Miller, Stowers Institute.

Drug resistance is a major obstacle in cancer treatment – leading to relapse for many patients. In a new study, published online April 20, 2020, in Nature Cell Biology, researchers from the Stowers Institute for Medical Research, Children’s Mercy Kansas City, and The University of Kansas Cancer Center report on a promising new strategy to overcome drug resistance in leukemia, using targeted doses of the widely-used chemotherapy drug doxorubicin.

The study’s researchers found that low doses of the anthracycline antibiotic doxorubicin inhibit the interaction between two molecular pathways that work closely together to promote tumor ...

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Synthetic Scaffolds to Heal Injured Tendons and Ligaments

The research hopes to improve the outcomes of sport injury surgeries. Credit: Pixabay

The research hopes to improve the outcomes of sport injury surgeries. Credit: Pixabay

Top biomedical engineering researcher develops synthetic scaffolds for tendon and ligament regeneration. Australia’s love of sport means it has one of the highest rates of knee anterior cruciate ligament (ACL) injury and reconstruction in the world.

Worldwide, the costs of tendon and ligament rupture repair and surgery revision represent tens of billions of dollars of the clinical orthopaedic market.

A team of biomedical engineering researchers from the University of Sydney, working with Columbia University’s Regenerative Engineering Laboratory and FAU Erlangen-Nurnberg Institute of Medical Biotechnology (Germany), are hoping to improve the outcomes of tendon and ligament repair by developing a new synthe...

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A Non-Invasive way of Monitoring Diabetes

Saliva could be used instead of blood to monitor diabetes in a method proposed in research involving the University of Strathclyde.
The test has been developed as an alternative to the current prevalent practice of monitoring blood glucose, which can be invasive, painful and costly.

Lab tests of the saliva process had an accuracy rate of 95.2%. The research shows promising results for monitoring diabetes, which affects an estimated 425 million people worldwide — around half of them undiagnosed.

The research has been published in the journal PLOS ONE. It also involved partners at the Federal University of Uberlandia in Minas Gerais, Brazil, the University of Vale do Paraíba in Sao Paolo, Brazil and the University of Saskatchewan in Canada.

Dr Matthew Baker, a Reader in Strathc...

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