Category Health/Medical

Study shows Lactate may Prompt Cancer Formation

cancer cell

A byproduct of glucose called lactate, used by every cell in the body, may also prompt a mutated cell to become cancerous, according to new research from the University of Colorado Anschutz Medical Campus.

The study was published Tuesday in the journal Frontiers in Oncology.
“We discovered that lactate is a catalyst that triggers a mechanism in mutated cells necessary to continue the cancer forming process,” said Iñigo San Millán, assistant professor of medicine at the University of Colorado School of Medicine and the University of Colorado Colorado Springs. “This opens a new door to better understand cancer at the metabolic level. It also means we might be able to target lactate with new therapies.”

Lactate is not a waste product but a major source of energy for t...

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Skin Cancer Suppressor found

DIRC3 regulates IGFBP5-dependent gene expression programmes involved in cancer.

A molecule that suppresses melanoma tumours has been identified. A promising route to develop new treatments for skin cancer has been identified by University of Bath scientists, who have found a molecule that suppresses melanoma tumour growth.

Although the research is at an early stage, the team hope that their work could help develop new ways to combat melanoma and potentially other cancers too.

The team from the University of Bath’s Department of Biology & Biochemistry were researching a group of ‘long non-coding RNAs’ (IncRNAs) with colleagues at the Ludwig Institute for Cancer Research at the University of Oxford, the Wellcome Sanger Institute and University of Lausanne, Switzerland.

IncRNA...

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Molecular Switch for Repairing Central Nervous System disorders

regenerative medicine researcher pipetting stem cells
A molecular switch has the ability to turn on a substance in animals that repairs neurological damage in disorders such as multiple sclerosis (MS)Mayo Clinic researchers discovered. The early research in animal models could advance an already approved Food and Drug Administration therapy and also could lead to new strategies for treating diseases of the central nervous system.

A molecular switch has the ability to turn on a substance in animals that repairs neurological damage in disorders such as multiple sclerosis (MS), Mayo Clinic researchers discovered. The early research in animal models could advance an already approved Food and Drug Administration therapy and also could lead to new strategies for treating diseases of the central nervous system.

Research by Isobel Scarisbr...

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Bandage Material helps Stop Bleeding Without Adhering to the Wound

Wundverband
Promotes healing and can subsequently be easliy removed: a new kind of bandage coated with silicone and carbon nanofibres. (Visualisations: Li Z et al. Nature Communications 2019)

Researchers from ETH Zurich and the National University of Singapore have developed a new kind of bandage that helps blood to clot and doesn’t stick to the wound. This marks the first time that scientists have combined both properties in one material.

“We did not actually plan this, but that is just how science works sometimes: you start researching one thing and end up somewhere else,” says ETH Professor Dimos Poulikakos...

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