Category Health/Medical

Inherited Pancreatic Cancer Risk Mutation Identified

Pancreatic Cancer Histology

The discovery of the previously unknown mutation could lead to routine testing of individuals with a strong family history of pancreatic cancer to determine if they carry the mutation, occurring in the gene known as RABL3. Scientists studying a highly cancer-prone family have identified a rare, inherited gene mutation that dramatically raises the lifetime risk of pancreatic and other cancers.

The discovery of the previously unknown mutation, reported in Nature Genetics by investigators from Dana-Farber/Brigham and Women’s Cancer Center, could lead to routine testing of individuals with a strong family history of pancreatic cancer to determine if they carry the mutation, occurring in the gene known as RABL3...

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New ‘Liquid Biopsy’ Blood Test improves Breast Cancer Diagnostics

ctDNA analysis in patients with early and locally advanced breast cancer before treatment and after completion of NAT.

Test could help avoid unnecessary surgeries; enable physicians to continuously monitor cancer. A new type of blood test for breast cancer could help avoid thousands of unnecessary surgeries and otherwise precisely monitor disease progression, according to a study led by the Translational Genomics Research Institute (TGen) and Mayo Clinic in Arizona.

TGen is an affiliate of City of Hope, which along with The Cancer Research UK Cambridge Institute at Cambridge University and the Biodesign Institute at Arizona State University (ASU) also contributed to this study.

Published today in the premier journal Science Translational Medicine, the study suggests that the te...

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This Designer Clothing Lets Users turn on Electronics while Turning Away Bacteria

fabric innovation
Purdue waterproof, breathable and antibacterial self-powered clothing is based on omniphobic triboelectric nanogenerators. 

New rainproof, stainproof technology turns clothing into self-powered remotes. Purdue University researchers have developed a new fabric innovation that allows wearers to control electronic devices through clothing.

“It is the first time there is a technique capable to transform any existing cloth item or textile into a self-powered e-textile containing sensors, music players or simple illumination displays using simple embroidery without the need for expensive fabrication processes requiring complex steps or expensive equipment,” said Ramses Martinez, an assistant professor in the School of Industrial Engineering and in the Weldon School of Biomedical Engine...

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Why Intense Light can Protect Cardiovascular Health

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Highlights
•Intense light-mediated cardioprotection requires endothelial-specific PER2
•Intense light-elicited PER2 transcriptionally reprograms the endothelium
•Endothelial PER2 regulates respiration and barrier function during hypoxia
•Studies of humans reveal intense light activates PER2-dependent metabolism

The light boosts a critical gene that strengthens blood vessels. Researchers at the University of Colorado Anschutz Medical Campus have found that intense light amplifies a specific gene that bolsters blood vessels and offers protection against heart attacks.

“We already knew that intense light can protect against heart attacks, but now we have found the mechanism behind it,” said the study’s senior author Tobias Eckle, MD, PhD, professor of anesthesiology at the University...

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