Category Health/Medical

Opposite effect: Protein widely known to Fight Tumors also Boosts Cancer Growth

UC San Diego researchers found that the PUMA protein works inside the cell’s mitochondria to switch energy production processes and stimulate cancer growth.
Credit: Xu Lab, UC San Diego

Researchers find evidence that genome ‘guardian’ can stimulate cancer. Researchers studying p53, the heralded cancer-fighting ‘guardian of the genome,’ found that the human protein also plays a role in promoting tumors, in addition to suppressing them. They found that the PUMA protein works inside the cell’s mitochondria to switch energy production processes and stimulate cancer growth. Search for a description of “p53” and it becomes clear that this human protein is widely known for its cancer-fighting benefits, leading to its renown as “the guardian of the genome.”

Scientists at the University of Ca...

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To Sleep, perchance to Heal: Newly discovered Gene governs need for slumber when Sick

This is an image of a fruit that fly has been infected with bacteria, showing nemuri expression (green) in the brain — a single neuron and its projections on either side of the brain.
Credit: Amita Sehgal, Perelman School of Medicine, University of Pennsylvania; Science

Direct link between illness and the need for more sleep. Humans spend nearly one-third of their lives in slumber, yet sleep is still one of biology’s most enduring mysteries. Little is known about what genetic or molecular forces drive the need to sleep – until now. In a study of over 12,000 lines of fruit flies, researchers from the Perelman School of Medicine at the University of Pennsylvania have found a single gene, called nemuri, that increases the need for sleep. These findings are published today in Science.

The ...

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Fasting Ramps up Human Metabolism, study shows

A study by the G0 Cell Unit and Kyoto University researchers suggests that fasting, which puts the body in ‘starvation mode,’ leads to fuel substitution, antioxidation, increased mitochondrial activation and altered signal transduction.
Credit: OIST

Fasting may help people lose weight, but new research suggests going without food may also boost human metabolic activity, generate antioxidants, and help reverse some effects of aging. Scientists at the Okinawa Institute of Science and Technology Graduate University (OIST) and Kyoto University identified 30 previously-unreported substances whose quantity increases during fasting and indicate a variety of health benefits.

“We have been researching aging and metabolism for many years and decided to search for unknown health effects in human ...

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Engineers Translate Brain Signals directly into Speech

Figure 1

Schematic of the speech reconstruction method.

Advance marks critical step toward brain-computer interfaces that hold immense promise for those with limited or no ability to speak. In a scientific first, Columbia neuroengineers have created a system that translates thought into intelligible, recognizable speech. By monitoring someone’s brain activity, the technology can reconstruct the words a person hears with unprecedented clarity. This breakthrough, which harnesses the power of speech synthesizers and artificial intelligence, could lead to new ways for computers to communicate directly with the brain...

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