Category Health/Medical

Spinal cord injuries affect an estimated 15 to 20 million people worldwide, often causing lasting impairments in movement, sensation and independence. Such injuries can be especially devastating when they occur at the level of the neck, where damaged spinal circuits disrupt signals that control the diaphragm, the main muscle used for breathing.

Despite advances in emergency care and rehabilitation, no approved therapies exist to rebuild the neurons and connections lost after a spinal cord injury. But new research from scientists at Gladstone Institutes offers hope for a regenerative treatment in the future.

The study, published in Science Translational Med...

Some physical injuries and neurological conditions can temporarily or permanently impair movement, leaving some people unable to speak, type on keyboards or use electronic devices. Brain-computer interfaces (BCIs), systems that can decode brain activity patterns and convert them into computer commands or written text, could be of great value for paralyzed patients.

Despite their potential, most of the best-performing BCIs developed ...

High-salt (HS) intake is a major global health concern, closely linked to hypertension and growing evidence of cognitive and emotional decline. Although salt is a routine part of daily diets, long-term overconsumption can negatively affect both the cardiovascular system and the central nervous system, underscoring the need for practical dietary strategies to mitigate these adverse health effects.

Prostaglandins (PGs) are lipid compounds derived from arachidonic acid (AA) that act as potent local hormones...

New Northwestern Medicine research published in Nature Communications suggests that a metabolite produced by gut bacteria when they digest dietary fiber can leave a lasting molecular imprint on intestinal cells, promoting immune tolerance and protecting against inflammatory bowel disease-like conditions long after exposure ends.

Yingzi Cong, Ph.D., the Stanley Gradowski Professor of Gastroenterology and a professor of Microbiology-Immunology and Pathology, was the senior and co-corresponding author of the study.

Investigators describe the findings as evidence that beneficial microbial metabolites may be able to “train” the intestinal lining to maintain immune tolerance over time.

“Our laboratory has...