Category Health/Medical

A nanopore device can contain different binding proteins. Once inside the pore, these proteins act as transducers to identify specific small molecules in a sample of body fluid.
Credit
Giovanni Maglia, University of Groningen

Scientists have designed a nanopore system that is capable of measuring different metabolites simultaneously in a variety of biological fluids, all in a matter of seconds. The electrical output signal is easily integrated into electronic devices for home diagnostics.

Measuring many metabolites or drugs in the body is complicated and time-consuming, and real-time monitoring is not usually possible. The ionic currents that pass through individual nanopores are emerging as a promising alternative to standard biochemical analysis...

UQ’s Dr Mario D. Garcia conducting one of the many experiments involved in the research.
Credit: The University of Queensland

A chemical compound found in common herbicides could help fight hospital-acquired human fungal pathogenic infections, which claim an estimated two million lives per year. A team of international researchers led by The University of Queensland has discovered that the chemical chlorimuron ethyl also targets a range of fungal infections that are potentially fatal to humans, particularly people undergoing treatments which place the immune system under stress.

Dr Luke Guddat, from UQ’s School of Chemistry and Molecular Biosciences, said the finding was very timely, given the growth in drug-resistant infections...

Nanoparticles to treat Snakebites

Venomous snakebites affect 2.5 million people, and annually cause more than 100,000 deaths and leave 400,000 individuals with permanent physical and psychological trauma each year. Researchers reporting in PLOS Neglected Tropical Diseases have now described a new approach to treating snake bites, using nanoparticles to bind to venom toxins and prevent the spread of venom through the body.

The standard treatment for snakebites is the intravenous administration of IgG immune molecules that recognize venoms. However, such antivenom therapies must be administered quickly – and by trained healthcare workers – to be effective and are highly specific to particular venoms...

Analyzing data from more than 400,000 people, researchers at Washington University School of Medicine in St. Louis have found that consuming one to two drinks four or more times per week — an amount deemed healthy by current guidelines — increases the risk of premature death by 20 percent.

At any age, daily drinkers 20% more likely to die prematurely than less frequent drinkers. Drinking a daily glass of wine for health reasons may not be so healthy after all, suggests a new study from Washington University School of Medicine in St. Louis.

Analyzing data from more than 400,000 people ages 18 to 85, the researchers found that consuming 1 to 2 drinks four or more times per week – an amount deemed healthy by current guidelines – increases the risk of premature death by 20%, compared with ...