Category Health/Medical

What came first, the chicken or the egg? Or both?
Credit: © olhastock / Fotolia

The “chicken or egg” paradox was first proposed by philosophers in Ancient Greece to describe the problem of determining cause-and-effect. Now, a team of physicists from The University of Queensland and the NÉEL Institute has shown that, as far as quantum physics is concerned, the chicken and the egg can both come first.

Dr Jacqui Romero from the ARC Centre of Excellence for Engineered Quantum Systems said that in quantum physics, cause-and-effect is not always as straightforward as one event causing another. “The weirdness of quantum mechanics means that events can happen without a set order,” she said. “Take the example of your daily trip to work, where you travel partly by bus and partly by train...

Myocardial Infarction Produces Sustained Proinflammatory Endothelial Activation in Remote Arteries

Cells and platelets stick inside arteries, increase risk after initial attack. Doctors have long known that in the months after a heart attack or stroke, patients are more likely to have another attack or stroke. Now, a paper in the Journal of the American College of Cardiology explains what happens inside blood vessels to increase risk – and suggests a new way to treat it.

Heart attacks in mice caused inflammatory cells and platelets to more easily stick to the inner lining of arteries throughout the body – and particularly where there was already plaque, according to the paper...

Illustration of a neutrophil cell membrane-coated nanoparticle.
Credit: Qiangzhe Zhang/Nature Nanotechnology

Engineers at the University of California San Diego have developed neutrophil “nanosponges” that can safely absorb and neutralize a variety of proteins that play a role in the progression of rheumatoid arthritis. Injections of these nanosponges effectively treated severe rheumatoid arthritis in two mouse models. Administering the nanosponges early on also prevented the disease from developing.

“Nanosponges are a new paradigm of treatment to block pathological molecules from triggering disease in the body,” said senior author Liangfang Zhang, a nanoengineering professor at the UC San Diego Jacobs School of Engineering...

During breast cancer, some cancer cells will leave the tumor to invade into nearby tissues. In this new paper, Salk scientists find that the gene Sox10 is important in activating this local invasion. Left panel: Significant numbers of invasive cancer cells with Sox10 (red) in them can be found outside of the tumor (green cells, outlined). Right panel shows the invasive cells’ proximity to blood vessels (white).
Credit: Salk Institute

A team at the Salk Institute has identified a master switch that appears to control the dynamic behavior of tumor cells that makes some aggressive cancers so difficult to treat. The gene Sox10 directly controls the growth and invasion of a significant fraction of hard-to-treat triple-negative breast cancers.

Recently, the Salk lab led by Professor Geoffrey Wa...