Category Health/Medical

These microcarriers may offer an entirely different approach to treating solid human tumors of numerous pathologic subtypes by delivering their encapsulated drug cargo to a tumor and protecting against collateral tissue damage. These multilayer capsules show three traits that have been difficult to achieve in a single entity. They have good imaging contrast that allows detection with low-power ultrasound, they can stably and efficiently encapsulate the cancer drug doxorubicin, and both a low- and higher-power dose of ultrasound can trigger the release of that cargo.

These 3 features create a guided drug delivery system to target solid tumors...

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A hormone responsible for controlling iron metabolism helps fight off a severe form of bacterial pneumonia, and that discovery may offer a simple way to help vulnerable patients. Hepcidin, is produced in the liver and limits the spread of the bacteria by hiding the iron in the blood that the bacteria need to survive and grow. Stimulating hepcidin production in patients who do not produce it well, such as people with iron overload or liver disease, may help their bodies effectively starve the bacteria to death...

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A group of researchers have made the first iron-based molecule capable of emitting light. This could contribute to the development of affordable and environmentally friendly materials for e.g. solar cells, light sources and displays. For over 50 years, chemists have developed metal-based dye molecules for a wide range of different applications, such as displays and solar cells. This would ideally involve common and environmentally friendly metals like iron, but despite a number of attempts no one has been able to develop an iron-based dye molecule that can emit light until now. Researchers around the world have therefore instead largely had to resort to various rare and precious metals, such as ruthenium, which have more easily provided the desired properties.

Thro...

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Scientists now reveal how viruses disable bacterial immune systems. For many bacteria, one line of defense against viral infection is a sophisticated RNA-guided “immune system” called CRISPR-Cas. At the center of this system is a surveillance complex that recognizes viral DNA and triggers its destruction...

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