Category Health/Medical

Detecting multiple cancers and other diseases from a single blood sample

Bloodtest
The new method, called MethylScan, works by analyzing cell-free DNA (cfDNA), tiny fragments of genetic material released into the blood when cells die.

UCLA scientists have developed a simple and cost-effective blood test that, in early studies, shows promise in detecting multiple cancers, various liver conditions and organ abnormalities simultaneously by analyzing DNA fragments circulating in the bloodstream. The test, described in the journal Proceedings of the National Academy of Sciences, could offer a powerful and more affordable approach to early disease detection and comprehensive health monitoring.

“Early detection is crucial,” said Dr...

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Biomarker test may improve risk assessment for HPV-related throat cancer

Dr Catherine Haring with a HPV biomarker test sample

Researchers at The Ohio State University Comprehensive Cancer Center—Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC—James) are advancing the understanding of a promising blood test that could personalize treatment and surveillance for patients with human papillomavirus (HPV)-associated throat cancer. The research, published in JAMA Otolaryngology—Head and Neck Surgery, explores how a blood-based test, circulating tumor HPV DNA (ctDNA), changes before and after surgery. The study explores how tumor biology and patient factors influence ctDNA levels. The findings provide important new insight into how this ctDNA test can be used along with pathology reports to improve risk assessment and personalize treatment plans.

“We know that more than 90% ...

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Long COVID is associated with increased risk of cardiovascular disease

Photo: Getty Images
Photo: Getty Images

People with long COVID are at increased risk of developing cardiovascular disease, according to a new study from Karolinska Institutet published in eClinicalMedicine. The results show that the risk of conditions such as cardiac arrhythmias and coronary artery disease is higher even among those who were not hospitalized during the acute infection.

Long COVID has become an increasingly significant health problem worldwide, and a growing number of studies suggest that the condition can lead to secondary cardiovascular diseases. To date, research has mainly focused on people who were hospitalized, while the risks for those who stayed at home or were treated at a GP are less well known...

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Organ-on-a-chip technology replicates decades of human aging in just four days

An array of microfluidic chips with circuit-like patterns on a metal wafer, illuminated in blue, pink, and yellow light.
A prototype wafer shows various configurations that the Stahl lab tested before settling on their current design. UC Berkeley photo by Mathew Burciaga

Over one billion people worldwide are over 60, and the population is projected to more than double by 2050. But as more people live into their 60s, 70s, and 80s, health care systems across the globe may face new challenges as they attempt to manage associated increases in age-related disease.

Metabolic biologist Andreas Stahl and preeminent longevity researcher Irina Conboy argue that the graying of the global population underscores the need to understand aging as a biological process, and how it might be slowed or reversed...

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