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    Category Health/Medical

    PINK1 protein crucial for removing broken-down energy reactors

    August 12, 2015, Categories  Health/Medical, Biology/Biotechnology

    PINK1 and parkin are key regulators of mitochondrial quality control. Credit: http://www.sciencedirect.com/.../pii/S0166223614000435

    PINK1 and parkin are key regulators of mitochondrial quality control. Credit: http://www.sciencedirect.com/…/pii/S0166223614000435

    >> potential new pathway to treat ALS, other diseases. When mitochondia are damaged, they leak destructive molecules that can cause substantial harm and eventually kill brain cells. PINK1, a protein implicated in Parkinson’s disease is critical for helping cells get rid of dysfunctional mitochondria, by triggering an intricate process called mitophagy that breaks down and removes damaged mitochondria from the cell.

    “PINK1 is a flag of damaged mitochondria,” said Richard Youle, Ph.D., the head of the Biochemistry Section of NINDS. “It identifies which mitochondria need to be eliminated to keep cells healthy...

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    Chitin of Insects and Crustaceans has been found to be active against pathogenic microorganisms

    August 11, 2015, Categories  Health/Medical, Biology/Biotechnology

    New Antibacterial Drug to Be Created At KFU ,medicine, research, medication, biology

    KFU’s researchers in cooperation with the Kazan Research Institute of Epidemiology and Microbiology and the Bioengineering Center of the Russian Academy of Sciences proved the effectiveness of biopolymers against pathogenic microorganisms. Подробности: http://kpfu.ru/eng/news-eng/new-antibacterial-drug-to-be-created-at-kfu-143092.html Любое использование материалов допускается только при наличии гиперссылки на портал КФУ (kpfu.ru)

    The study specifically concentrated on chitosan extracted from chitin in the carapaces of insects and crustaceans. “We found that some forms of chitosan are toxic...

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    New Combination Rx effective against Melanoma Skin Metastases

    August 11, 2015, Categories  Health/Medical, Biology/Biotechnology

    Metastatic melanoma: positron emission tomographic (PET)/computed tomography (CT) images. A-C, PET/CT of the head and neck after recurrence of malignant melanoma reveals increased FDG uptake spanning from the nose, left malar cheek, to the left ear, which represents a large melanoma (8.5 cm) and multiple additional in-transit metastases. E-G, Three months after restarting intralesional interleukin 2, imiquimod, and a topical retinoid, there is resolution of the enhancing lesions. D, At initial presentation, PET/CT image (patient 8) shows increased FDG uptake in the skin and subcutaneous tissues of the back of right forearm, consistent with biopsy-proven melanoma (18- × 6-cm plaque). H, At 5 months posttreatment, no hypermetabolic lesion is identified.

    Metastatic melanoma: positron emission tomographic (PET)/computed tomography (CT) images. A-C, PET/CT of the head and neck after recurrence of malignant melanoma reveals increased FDG uptake spanning from the nose, left malar cheek, to the left ear, which represents a large melanoma (8.5 cm) and multiple additional in-transit metastases. E-G, Three months after restarting intralesional interleukin 2, imiquimod, and a topical retinoid, there is resolution of the enhancing lesions. D, At initial presentation, PET/CT image (patient 8) shows increased FDG uptake in the skin and subcutaneous tissues of the back of right forearm, consistent with biopsy-proven melanoma (18- × 6-cm plaque). H, At 5 months posttreatment, no hypermetabolic lesion is identified. Creit: 10.1016/j.jaad.2015.06.060

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    New Breath Test Shows Possible Biomarker for Early-Stage Liver Disease Diagnosis

    August 11, 2015, Categories  Health/Medical, Biology/Biotechnology

     

    A natural compound, limonene, found in oranges and lemons, could be indicative in early-stage diagnosis of liver disease. Patients with this illness do not often present with symptoms until the disease is advanced. Even then diagnosis is difficult and the symptoms and signs are often general and can be mistaken for other pathologies. For advanced cirrhosis liver,transplant is the only treatment.

    In the UK liver disease has risen sharply over the past few decades and is the 3rd biggest cause of premature mortality, with 3/4 of liver deaths due to alcohol. Patients do not often present with symptoms until the disease is advanced.

    The R enantiomer of limonene smells like oranges. The S enantiomer smells like lemons.

    The R enantiomer of limonene smells like oranges. The S enantiomer smells like lemons. Credit: https://jahschem.wikispaces.com/stereochem+in+biology

    The Molec...

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