Category Technology/Electronics

Detecting Single Molecules and Diagnosing Diseases with a Smartphone

© Lennart Grabenhorst / Tinnefeld Group

Researchers show that the light emitted by a single molecule can be detected with a low-cost optical setup. Their prototype could facilitate medical diagnostics. Biomarkers play a central role in the diagnosis of disease and assessment of its course. Among the markers now in use are genes, proteins, hormones, lipids and other classes of molecules. Biomarkers can be found in the blood, in cerebrospinal fluid, urine and various types of tissues, but most of them have one thing in common: They occur in extremely low concentrations, and are therefore technically challenging to detect and quantify.

Many detection procedures use molecular probes, such as antibodies or short nucleic-acid sequences, which are designed to bind to specific biomarkers...

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New Machine Learning Theory raises Questions about Nature of Science

PPPL physicist Hong Qin in front of images of planetary orbits and computer code (Photo by Elle Starkman)

A novel computer algorithm, or set of rules, that accurately predicts the orbits of planets in the solar system could be adapted to better predict and control the behavior of the plasma that fuels fusion facilities designed to harvest on Earth the fusion energy that powers the sun and stars.

The algorithm, devised by a scientist at the U.S. Department of Energy’s (DOE) Princeton Plasma Physics Laboratory (PPPL), applies machine learning, the form of artificial intelligence (AI) that learns from experience, to develop the predictions...

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Nanowire could provide a Stable, easy-to-make Superconducting Transistor

superconducting nanowire
MIT researchers are developing a superconducting nanowire, which could enable more efficient superconducting electronics.
Credits:Image: Christine Daniloff, MIT

Superconductors—materials that conduct electricity without resistance—are remarkable. They provide a macroscopic glimpse into quantum phenomena, which are usually observable only at the atomic level. Beyond their physical peculiarity, superconductors are also useful. They’re found in medical imaging, quantum computers, and cameras used with telescopes.

But superconducting devices can be finicky. Often, they’re expensive to manufacture and prone to err from environmental noise. That could change, thanks to research from Karl Berggren’s group in the Department of Electrical Engineering and Computer Science.

The researche...

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Silicon chip provides low cost solution to help Machines See the World Clearly

Swivel Chair
Exercise ball & screen at 40m – picture taken using a 32×16 pixel sensor (2mmx2.5mm sensor size)

Researchers in Southampton and San Francisco have developed the first compact 3D LiDAR imaging system that can match and exceed the performance and accuracy of most advanced, mechanical systems currently used.

3D LiDAR can provide accurate imaging and mapping for many applications; it is the “eyes” for autonomous cars and is used in facial recognition software and by autonomous robots and drones. Accurate imaging is essential for machines to map and interact with the physical world but the size and costs of the technology currently needed has limited LIDAR’s use in commercial applications.

Now a team of researchers from Pointcloud Inc in San Francisco and the University of Southampton...

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