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Natural Compound found in Broccoli reawakens the Function of Potent Tumor Suppressor

Reactivation of PTEN tumor suppressor for cancer treatment through inhibition of a MYC-WWP1 inhibitory pathway. Science, 2019; 364 (6441): eaau0159 DOI: 10.1126/science.aau0159

Finding offers potential novel approach to cancer treatment and prevention. Long associated with decreased risk of cancer, broccoli and other cruciferous vegetables – the family of plants that also includes cauliflower, cabbage, collard greens, Brussels sprouts and kale – contain a molecule that inactivates a gene known to play a role in a variety of common human cancers...

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Shrinking Moon may be Generating Moonquakes

Evidence for moonquakes on Lee-Lincoln fault scarp
The Taurus-Littrow valley is the location of the Apollo 17 landing site (asterisk). Cutting across the valley, just above the landing site, is the Lee-Lincoln fault scarp. Movement on the fault was the likely source of numerous moonquakes that triggered events in the valley. 1) Large landslides on of slopes of South Massif draped relatively bright rocks and dust (regolith) on and over the Lee-Lincoln scarp. 2) Boulders rolled down the slopes of North Massif leaving tracks or narrow troughs in the regolith on the slopes of North Massif. 3) Landslides on southeastern slopes of the Sculptured Hills.
Credits: NASA/GSFC/Arizona State University/Smithsonian

A new analysis suggests that the moon is actively shrinking and producing moonquakes along thousands of cliffs called thrust faults spr...

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Plastic gets a do-over: Breakthrough Discovery Recycles Plastic from the Inside

Unlike conventional plastics, the monomers of PDK plastic could be recovered and freed from any compounded additives simply by dunking the material in a highly acidic solution. (Credit: Peter Christensen et al./Berkeley Lab)

Scientists have made a next-generation plastic that can be recycled again and again into new materials of any color, shape, or form. Because plastics contain various additives, like dyes, fillers, or flame retardants, very few plastics can be recycled without loss in performance or aesthetics. Even the most recyclable plastic, PET – or poly(ethylene terephthalate) – is only recycled at a rate of 20-30%, with the rest typically going to incinerators or landfills, where the carbon-rich material takes centuries to decompose.

Now a team of researchers at the U.S...

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Engineers make Injectable Tissues a Reality

Doctoral student Mohamed Gamal uses a newly developed cell encapsulation device.
Credit: Nathan Skolski, UBC Okanagan

New device encases delicate cells into protective microgels. A simple injection that can help regrow damaged tissue has long been the dream of physicians and patients alike. A new study from researchers at UBC Okanagan moves that dream closer to reality with a device that makes encapsulating cells much faster, cheaper and more effective.

“The idea of injecting different kinds of tissue cells is not a new one,” says Keekyoung Kim, assistant professor of engineering at UBC Okanagan and study co-author. “It’s an enticing concept because by introducing cells into damaged tissue, we can supercharge the body’s own processes to regrow and repair an injury.”

Kim says eve...

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