‘Good’ Bacteria Show Promise for Clinical Treatment of Crohn’s Disease, Ulcerative Colitis

Good' bacteria show promise for clinical treatment of Crohn's disease, ulcerative  colitis
Credit: CC0 Public Domain

A new study published in Nature Communications demonstrates that a consortium of bacteria designed to complement missing or underrepresented functions in the imbalanced microbiome of inflammatory bowel disease (IBD) patients, prevented and treated chronic immune-mediated colitis in humanized mouse models. The study’s senior author, Balfour Sartor, MD, Midget Distinguished Professor of Medicine, Microbiology and Immunology, Co-Director of the UNC Multidisciplinary IBD Center, said the results are encouraging for future use treating Crohn’s disease and ulcerative colitis patients.

“The idea with this treatment is to restore the normal function of the protective bacteria in the gut, targeting the source of IBD, instead of treating its symptoms with traditional...

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New technique breaks the mold for 3D printing medical implants

A tiny and intricate biomedical structure being held on a fingertip of a gloved hand

How to use glue and a high school 3D printer to create tiny implants for tissue engineering. Researchers have flipped traditional 3D printing to create some of the most intricate biomedical structures yet, advancing the development of new technologies for regrowing bones and tissue.

The emerging field of tissue engineering aims to harness the human body’s natural ability to heal itself, to rebuild bone and muscle lost to tumours or injuries.

A key focus for biomedical engineers has been the design and development of 3D printed scaffolds that can be implanted in the body to support cell regrowth.

But making these structures small and complex enough for cells to thrive remains a significant challenge.

Enter a RMIT University-led research team, collaborating with clinicians a...

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Extreme Greenhouse Effect Heated up the Young Earth

Greenhouse gases trap energy from the sun in the lower atmosphere. Without these gases, the Earth would be a chilly minus 18 degrees Centigrade. In contrast, the atmosphere on Mars is almost entirely made of carbon dioxide, but it has a very thin atmosphere and little to no methane or water vapour, producing a weaker greenhouse effect. Credit: NASA

Very high atmospheric CO2 levels can explain the high temperatures on the still young Earth three to four billion years ago. At the time, our Sun shone with only 70 to 80 percent of its present intensity. Nevertheless, the climate on the young Earth was apparently quite warm because there was hardly any glacial ice. This phenomenon is known as the ‘paradox of the young weak Sun...

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Global Warming Already Responsible for 1 in 3 Heat-related Deaths

Sunrise in London, UK. Credit: Kasim Rashid/Flickr

New estimates suggest Central and South America and South-East Asia most affected regions. Between 1991 and 2018, more than a third of all deaths in which heat played a role were attributable to human-induced global warming, according to a new article in Nature Climate Change.

The study, the largest of its kind, was led by the London School of Hygiene & Tropical Medicine (LSHTM) and the University of Bern within the Multi-Country Multi-City (MCC) Collaborative Research Network. Using data from 732 locations in 43 countries around the world it shows for the first time the actual contribution of human-made climate change in increasing mortality risks due to heat.

Overall, the estimates show that 37% of all heat-related deaths in the recent summer periods were attributable to the w...

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