Body’s Natural Pain Killers can be enhanced

cookie cutter with pills inside in colorful colors
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A study in cells and mice finds compound works with fewer side effects than opioids. Fentanyl, oxycodone, morphine—these substances are familiar to many as a source of both pain relief and the cause of a painful epidemic of addiction and death.

Scientists have attempted for years to balance the potent pain-relieving properties of opioids with their numerous negative side effects—with mostly mixed results.

Work by John Traynor, Ph.D., and Andrew Alt, Ph.D., and their team at the University of Michigan Edward F. Domino Research Center, funded by the National Institute on Drug Abuse, seeks to side-step these problems by harnessing the body’s own ability to block pain.

All opioid drugs—from poppy-derived opium to heroin—work on receptors that are naturally prese...

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Scientists glimpse signs of a Puzzling State of Matter in a Superconductor

SLAC scientists used an improved X-ray technique to explore exotic states of matter in an unconventional superconductor that conducts electricity with 100% efficiency at relatively high temperatures. They glimpsed the signature of a state known as pair density waves (PDW), and confirmed that it intertwines with another phase known as charge density wave (CDW) stripes – wavelike patterns of higher and lower electron density in the material. CDWs, in turn, are created when spin density waves (SDWs) emerge and intertwine. (Jun-Sik Lee/SLAC National Accelerator Laboratory)

Known as ‘pair-density waves,’ it may be key to understanding how superconductivity can exist at relatively high temperatures...

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The Science of Spin: Asteroseismologists confirm older stars rotate faster than expected

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Credit: Mark Garlick/University of Birmingham

Stars spin faster than expected as they age according to a new study led by scientists at the University of Birmingham which uses asteroseismology to shed new light on this emerging theory.

All stars, like the Sun, are born spinning. As they grow older, their spin slows down due to magnetic winds in a process called ‘magnetic braking’. Research published in 2016 by scientists at Carnegie Observatories delivered the first hints that stars at a similar stage of life as the Sun were spinning faster than magnetic braking theories predicted. The results from this study were based on a method in which scientists pinpoint dark spots on the surface of stars and track them as they move with the stars’ spin...

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Laser Paintbrush used to Create Miniature Masterpieces

 The researchers used their new laser painting method to make a miniature version of Van Gogh’s painting “The Starry Night.”
Credit: Yaroslava Andreeva

Technique creates color on metal that can be changed, erased and rewritten. Researchers are blurring the lines between science and art by showing how a laser can be used to create artistic masterpieces in a way that mirrors classical paints and brushes. The new technique not only creates paint-like strokes of color on metal but also offers a way to change or erase colors.

“We developed a way to use a laser to create localized color on a metallic canvas using a technique that heats the metal to the point where it evaporates,” said research team leader Vadim Veiko from ITMO University in Russia...

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