Artificial Intelligence makes great Microscopes better than ever

Green streaks shoot off of a blue, purple and pink bulbous shape against a dark background of circles and curvy lines.
A representation of a neural network provides a backdrop to a fish larva’s beating heart. Illustration credit: Tobias Wüstefeld.

Machine learning helps some of the best microscopes to see better, work faster, and process more data. Collaboration between deep learning experts and microscopy experts leads to an significantly improved data-intensive light-field microscopy method by using AI and ground-truthing it with light-sheet microscopy. The result is the power of light-field microscopy available to biologists in near real time vs. days or weeks, AND the expansion of biologists’ ability to use this microscopy for many things more things requiring the most detailed observation.

To observe the swift neuronal signals in a fish brain, scientists have started to use a technique calle...

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Research Breakthrough in the Fight Against Cancer

The advantage of PACs over other therapies.
The advantage of PACs over other therapies. Courtesy: S. Thai Thayumanavan

Latest advance in targeted delivery of therapeutic proteins. A team of researchers at the Center for Bioactive Delivery at the University of Massachusetts Amherst’s Institute for Applied Life Sciences has engineered a nanoparticle that has the potential to revolutionize disease treatment, including for cancer. This new research, which appears today in Angewandte Chemie, combines two different approaches to more precisely and effectively deliver treatment to the specific cells affected by cancer.

Two of the most promising new treatments involve delivery of cancer-fighting drugs via biologics or antibody-drug conjugates (ADCs). Each has its own advantages and limitations...

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Physicists describe New Type of code Aurora

New aurora
Diffuse auroral erasers

Discovery comes from reanalysis of two-decade-old video. The famed northern and southern lights have been studied for millennia, but they still hold secrets. Physicists describe a new phenomenon they call ‘diffuse auroral erasers,’ in which patches of the background glow are blotted out, then suddenly intensify and reappear.

For millennia, humans in the high latitudes have been enthralled by auroras — the northern and southern lights. Yet even after all that time, it appears the ethereal, dancing ribbons of light above Earth still hold some secrets.

In a new study, physicists led by the University of Iowa report a new feature to Earth’s atmospheric light show...

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Alzheimer’s Study: A Mediterranean Diet might protect against Memory Loss and Dementia

Source: Sonyakamoz, adobe stock

Alzheimer’s disease is caused by protein deposits in the brain and the rapid loss of brain matter. But a Mediterranean diet rich in fish, vegetables and olive oil might protect the brain from these disease triggers. In Alzheimer’s disease, neurons in the brain die. Largely responsible for the death of neurons are certain protein deposits in the brains of affected individuals: So-called beta-amyloid proteins, which form clumps (plaques) between neurons, and tau proteins, which stick together the inside of neurons. The causes of these deposits are as yet unclear. In addition, a rapidly progressive atrophy, i.e. a shrinking of the brain volume, can be observed in affected persons...

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