‘Zombie’ Genes? Research shows some Genes Come to Life in the Brain after Death

Post-mortem changes may shed light on important brain studies. In the hours after we die, certain cells in the human brain are still active. Some cells even increase their activity and grow to gargantuan proportions, according to new research from the University of Illinois Chicago.

In a newly published study in the journal Scientific Reports, the UIC researchers analyzed gene expression in fresh brain tissue — which was collected during routine brain surgery — at multiple times after removal to simulate the post-mortem interval and death. They found that gene expression in some cells actually increased after death.

These ‘zombie genes’ — those that increased expression after the post-mortem interval — were specific to one type of cell: inflammatory cells called glial cells...

Read More

A simple way to Turn 2D Drawings into 3D Objects

A team of researchers affiliated with several institutions in South Korea has developed a simple method for converting 2D drawings to 3D objects. In their paper published in the journal Science Advances, the group describes their technique and possible uses for it.

Over the past several decades, 3D printing has become a popular way to create three-dimensional objects in a relatively simple manner. Such printing allows for on-demand supply of simple products. In this new effort, the researchers have developed another way to create 3D objects without the need for a printer.

The technique involves hand-drawing (or conventionally printing) a 2D image on an object using a special pen with special ink and then submerging the object in a tub of water...

Read More

New Light on Baryonic Matter and Gravity on Cosmic Scales

The presence of ionized gas around galaxies with moves with them leaves a trace in the microwave background radiation (left panel) which can be detected knowing the pattern of velocities of the galaxies provided by the map of fluctuations in their redshift (right panel). Credit: Carlos Hernández-Monteagudo (IAC).
The presence of ionized gas around galaxies with moves with them leaves a trace in the microwave background radiation which can be detected knowing the pattern of velocities of the galaxies provided by the map. Credit: Carlos Hernández-Monteagudo (IAC).

Scientists estimate that dark matter and dark energy together are some 95% of the gravitational material in the universe while the remaining 5% is baryonic matter, which is the “normal” matter composing stars, planets and living beings. However, for decades, almost one-half of this matter has not been found. Now, using a new technique, a team including researchers from the Instituto de Astrofísica de Canarias (IAC) has shown that this “missing” baryonic matter fills the space between galaxies as hot, low-density gas...

Read More

New Strategy for Fighting Brain Cancer

Cancer image

Most people relate cholesterol to heart health, but it is also a critical component in the growth and spread of brain cancer. VCU Massey Cancer Center researcher Suyun Huang, Ph.D., recently discovered how cholesterol becomes dysregulated in brain cancer cells and showed that the gene responsible for it could be a target for future drugs.

The mean survival of patients with the most common and aggressive type of brain cancer, glioblastoma multiforme (GBM), is 14 months. The need to find new, effective treatments is urgent and has driven Huang, a member of the Cancer Biology research program at Massey, to detail the workings of numerous genes, proteins, enzymes and other cellular components that contribute to brain cancer growth...

Read More