World-first discovery paves way to New Cancer Treatment

Cancer

Australian researchers have discovered a new way to target an aggressive childhood cancer, neuroblastoma, one of the most common and dangerous cancers in young children.

The discovery may also have important implications for some other aggressive cancers in children, including certain brain tumours, as well as some adult cancers, including ovarian and prostate cancer.

The new research, led by scientists at Children’s Cancer Institute and published in Nature Communications, has discovered that a cellular protein called ALYREF plays a crucial role in accelerating the effects of the cancer driver gene, MYCN, in neuroblastoma.

Scientists have known for some time that the one third of children with neuroblastoma who have very high levels of MYCN in their cancer cells have a much p...

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A Bio-inspired Mechano-Photonic Artificial Synapse

A bioinspired mechano-photonic artificial synapse
Biological tactile/visual neurons and mechano-photonic artificial synapse. (A) Schematic illustrations of biological tactile/visual sensory system. (B) Schematic diagram of the mechano-photonic artificial synapse based on graphene/MoS2 (Gr/MoS2) heterostructure. (i) Top-view scanning electron microscope (SEM) image of the optoelectronic transistor; scale bar, 5 μm. The cyan area indicates the MoS2 flake, while the white strip is graphene. (ii) Illustration of charge transfer/exchange for Gr/MoS2 heterostructure. (iii) Output mechano-photonic signals from the artificial synapse for image recognition. Credit: Science Advances, doi: 10.1126/sciadv.abd9117

Multifunctional and diverse artificial neural systems can incorporate multimodal plasticity, memory and supervised learning functions ...

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Supernova Simulations reveal how Stellar Explosions Shape Debris Clouds

image of a supernova
A supernova creates a cloud of debris that bears an imprint of the explosion. In this visualization of the simulation data, one quarter of the remnant’s outer shell has been removed to reveal the clumps of matter within (colors denote different materials). Credit: Reproduced from Ref. 1 by permission of the AAS.

Astronomers are now in a better position to interpret observations of supernova remnants thanks to computer simulations of these cataclysmic events by RIKEN astrophysicists.

When certain types of stars die, they go out in a blaze of glory—an incredibly powerful explosion known as a supernova. One of the most common forms of supernova, typeIa, starts with a dense white dwarf star that has burned up its hydrogen fuel...

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New Class of Versatile, High-Performance Quantum Dots Primed for Medical Imaging, Quantum Computing

A new, highly versatile class of quantum dots excel as single-photon emitters, with applications in biomedical imaging, quantum communication, cybersecurity, and many other fields. Zachary (Zack) Robinson (left) and Vladimir Sayevich (right) are part of the team that has developed these infrared-emitting quantum dots.

A new class of quantum dots deliver a stable stream of single, spectrally tunable infrared photons under ambient conditions and at room temperature, unlike other single photon emitters. This breakthrough opens a range of practical applications, including quantum communication, quantum metrology, medical imaging and diagnostics, and clandestine labeling.

“The demonstration of high single-photon purity in the infrared has immediate utility in areas such as quantum key di...

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