Hydrogel Injection may change the way the Heart Muscle Heals after a Heart Attack

NUI Galway
Graphic of heart and injectable hydrogel. Photo: CÚRAM

Researchers at CÚRAM, the SFI Research Centre for Medical Devices based at National University of Ireland Galway, and BIOFORGE Lab, at the University of Valladolid in Spain, have developed an injectable hydrogel that could help repair and prevent further damage to the heart muscle after a heart attack.

The results of their research have just been published in the journal Science Translational Medicine.

Myocardial infarction or heart disease is a leading cause of death due to the irreversible damage caused to the heart muscle (cardiac tissue) during a heart attack. The regeneration of cardiac tissue is minimal so that the damage caused cannot be repaired by itself...

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4D Bioengineering materials Bend, Curve like Natural Tissue

4-D hydrogel-based materials can undergo multiple conformational shape changes in response to environmental cues. (Image: Aixiang Ding)
4D hydrogel-based materials can undergo multiple conformational shape changes in response to environmental cues. (Image: Aixiang Ding)

Researchers have developed new 4D hydrogels – 3D materials that have the ability to change shape over time in response to stimuli – that can morph multiple times in a preprogrammed or on-demand manner in response to external trigger signals.

Tissue engineering has long-depended on geometrically static scaffolds seeded with cells in the lab to create new tissues and even organs. The scaffolding material — usually a biodegradable polymer structure — is supplied with cells and the cells, if supplied with the right nutrients, then develop into tissue as the underlying scaffold biodegrades...

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Astronomers Accurately Measure the Temperature of Red Supergiant Stars

A dark background. An orange amorphous cloud.
Betelgeuse. The red supergiant appears as a red starburst between two orange clouds. © 2021 Andrew Klinger

Red supergiants are a class of star that end their lives in supernova explosions. Their lifecycles are not fully understood, partly due to difficulties in measuring their temperatures. For the first time, astronomers develop an accurate method to determine the surface temperatures of red supergiants.

Stars come in a wide range of sizes, masses and compositions. Our sun is considered a relatively small specimen, especially when compared to something like Betelgeuse which is known as a red supergiant...

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A Weak Heart makes a Suffering Brain

Evidence of disturbed gene activity in the brain as a result of heart problems. Researchers at the German Center for Neurodegenerative Diseases (DZNE), the University Medical Center Göttingen (UMG) and the German Center for Cardiovascular Research (DZHK) come to this conclusion based on laboratory studies. They consider that they have found a possible cause for the increased risk of dementia in people with heart problems. In mice, a specific drug which is known to affect gene activity alleviated the mental deficits. The involved experts see these results as potential approaches for therapies. The study data are published in the scientific journal EMBO Molecular Medicine.

In Germany, about four million people are affected by what is called “heart failure”: Their heart muscle is too...

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