Tomatoes offer Affordable Source of Parkinson’s disease Drug

Metabolic engineering of tomato fruit enriched in L-DOPA
Author links open overlay panelDarioBreitelacPaulBrettaSalehAlseekhbAlisdair R.FerniebEugenioButelliaCathieMartina

Scientists have produced a tomato enriched in the Parkinson’s disease drug L-DOPA in what could become a new, affordable source of one of the world’s essential medicines.

The development of the genetically modified (GM) tomato has implications for developing nations where access to pharmaceutical drugs is restricted.

This novel use of tomato plants as a natural source of L-DOPA also offers benefits for people who suffer adverse effects — including nausea and behavioral complications — of chemically synthesised L-DOPA .

Tomato — was chosen as a widely cultivated crop that can be used for scaled up production a...

Read More

Stretchable Micro-Supercapacitors to Self-power Wearable devices

A team of international researchers, led by Huanyu “Larry” Cheng, Dorothy Quiggle Career Development Professor in Penn State’s Department of Engineering Science and Mechanics, has developed a self-powered, stretchable system that will be used in wearable health-monitoring and diagnostic devices.
 IMAGE: PENN STATE COLLEGE OF ENGINEERING

A stretchable system that can harvest energy from human breathing and motion for use in wearable health-monitoring devices may be possible, according to an international team of researchers, led by Huanyu “Larry” Cheng, Dorothy Quiggle Career Development Professor in Penn State’s Department of Engineering Science and Mechanics.

The research team, with members from Penn State and Minjiang University and Nanjing University, both in China, recently p...

Read More

Spiders in Space: Without Gravity, Light becomes key to Orientation

A black and white picture of a spider in its web in the experimental container on board the ISS
A specimen of the spider species Trichonephila clavipes on board the international space station ISS. (Photo: BioServe Space Technologies, University of Colorado Boulder

Humans have taken spiders into space more than once to study the importance of gravity to their web-building. What originally began as a somewhat unsuccessful PR experiment for high school students has yielded the surprising insight that light plays a larger role in arachnid orientation than previously thought.

The spider experiment by the US space agency NASA is a lesson in the frustrating failures and happy accidents that sometimes lead to unexpected research findings. The question was relatively simple: on Earth, spiders build asymmetrical webs with the center displaced towards the upper edge...

Read More

Hydrogel could open new path for Glaucoma Treatment without Drugs or Surgery

A microneedle less than a millimeter in length is used to inject a natural and biodegradable polymer material into a structure in the eye. The material forms a hydrogel that holds open a pathway to release pressure from the eye. (Credit: Gary Meek, Georgia Tech)

Researchers have developed a potential new treatment for the eye disease glaucoma that could replace daily eye drops and surgery with a twice-a-year injection to control the buildup of pressure in the eye. The researchers envision the injection being done as an office procedure that could be part of regular patient visits.

The possible treatment, which could become the first non-drug, non-surgical, long-acting therapy for glaucoma, uses the injection of a natural and biodegradable material to create a viscous hydrogel — a wa...

Read More