Bringing Drugs to the brain with Nanoparticles to treat Neurodegenerative diseases

After several years of research on effective and safe nanoparticles, the research team will continue laboratory testing, targeting the delivery of active ingredients to other animal models with ultimate clinical applications.

Researchers from the Institut national de la recherche scientifique (INRS) have shown that nanoparticles could be used to deliver drugs to the brain to treat neurodegenerative diseases.

The blood-brain barrier is the main obstacle in treating neurodegenerative diseases such as Alzheimer and Parkinson. According to a recent study conducted by Jean-Michel Rabanel, a postdoctoral researcher under the supervision of Professor Charles Ramassamy, nanoparticles with specific properties could cross this barrier and be captured by neuronal cells...

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Large-area Flexible Organic Photodiodes can compete with Silicon devices

Georgia Tech principal research scientist Canek Fuentes-Hernandez holds rigid and flexible large-area organic photodiodes whose performance is comparable to that of silicon-based photodiodes. (Credit: Canek Fuentes-Hernandez, Georgia Tech)

The performance of flexible large-area organic photodiodes has advanced to the point that they can now offer advantages over conventional silicon photodiode technology, particularly for applications such as biomedical imaging and biometric monitoring that require detecting low levels of light across large areas.

The low-noise, solution-processed, flexible organic devices offer the ability to use arbitrarily shaped, large-area photodiodes to replace complex arrays that would be required with conventional silicon photodiodes, which can be expensive ...

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First Brown Dwarf discovered by Radio Observations confirmed

Artist’s impression of the cold brown dwarf BDR J1750+380

New research has led to the first direct discovery of a cold brown dwarf from its radio wavelength emission. Along with paving the way for future brown dwarf discoveries, this result is an important step towards applying radio astronomy to the exciting field of exoplanets.

A collaboration between the LOw Frequency ARray (LOFAR) radio telescope in Europe, the Gemini North telescope, and the NASA InfraRed Telescope Facility (IRTF), both on Maunakea in Hawai’i, has led to the first direct discovery of a cold brown dwarf from its radio wavelength emission. Along with paving the way for future brown dwarf discoveries, this result is an important step towards applying radio astronomy to the exciting field of exoplanets.

For th...

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Scientists create Hybrid Tissue construct for Cartilage Regeneration

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3D Bioprinted Highly Elastic Hybrid Constructs for Advanced Fibrocartilaginous Tissue Regeneration

Wake Forest Institute for Regenerative Medicine scientists (WFIRM) have developed a method to bioprint a type of cartilage that could someday help restore knee function damaged by arthritis or injury.

This cartilage, known as fibrocartilage, helps connect tendons or ligaments or bones and is primarily found in the meniscus in the knee. The meniscus is the tough, rubbery cartilage that acts as a shock absorber in the knee joint. Degeneration of the meniscus tissue affects millions of patients and arthroscopic partial meniscectomy is one of the most common orthopedic operations performed. Besides surgery, there is a lack of available treatment options.

In this latest proof-of-concept ...

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